Zagdańska J, Krakówka P, Polowiec Z
I Kliniki Gruźlicy i Chorób Pluc Instytutu Gruźlicy i Chorób Pluc.
Pneumonol Alergol Pol. 1992;60(1-2):55-62.
A case of sinus histiocytosis with generalized lymphadenopathy--Rosai-Dorfman disease--in a 54 year old male is presented. The diagnosis was made by biopsy of the lymph nodes and histopathological examination of the affected organ. Treatment with prednisone and cyclophosphamide induced clinical improvement. The diseases clinical advanced stage and organ localization and the immunosuppressive therapy resulted in a opportunistic infection--pneumocystidosis and death of the patient within half a year after starting of therapy.
本文报告一例54岁男性的窦性组织细胞增生伴全身淋巴结肿大——罗萨伊-多夫曼病。通过淋巴结活检及对受累器官进行组织病理学检查做出诊断。泼尼松和环磷酰胺治疗使临床症状有所改善。该疾病的临床晚期、器官定位以及免疫抑制治疗导致了机会性感染——肺孢子虫病，患者在开始治疗后半年内死亡。
