Buénerd Annie, Mathevet Patrice, Gengler Carole, Scoazec Jean-Yves, Berger Gérard
Service d'Anatomie et de Cytologie pathologiques, Hôpital Edouart Herriot, Lyon.
Ann Pathol. 2003 Jun;23(3):236-9.
We report the first case of placental site trophoblastic tumor following in vitro fertilization. A 32-year-old woman presented with a vaginal polyp diagnosed 11 months after a successful fertilization, resulting in the delivery of a term male baby, but followed by persistent amenorrhea. The diagnosis of PSTT was done on examination of the vaginal polyp and the curettage specimen and was confirmed after hysterectomy. The patient was well 30 months later. The value of initial metastases limited to the pelvis and the role of in vitro fertilization in the pathogenesis of the tumor are discussed.
我们报告首例体外受精后发生的胎盘部位滋养细胞肿瘤。一名32岁女性，在成功受精并足月分娩一名男婴后11个月，出现阴道息肉，随后持续闭经。通过对阴道息肉及刮宫标本检查诊断为胎盘部位滋养细胞肿瘤，子宫切除术后得以确诊。30个月后患者情况良好。本文讨论了初始转移局限于盆腔的情况以及体外受精在该肿瘤发病机制中的作用。
