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[儿童葡萄膜炎:约20例]

[Uveitis in children: about 20 cases].

作者信息

Laghmari M, Karim A, Guedira K, Ibrahimy W, Dahreddine M, Essakalli N H, Mohcine Z

机构信息

Service d'Ophtalmologie A, Hôpital des Spécialités, Rabat, Maroc.

出版信息

J Fr Ophtalmol. 2003 Jun;26(6):609-13.

Abstract

INTRODUCTION

Uveitis in children is rare: 3%-8% of all cases. It requires the same diagnostic and etiological processes as uveitis in adults, with additional difficulties at examination and a sometimes insidious progression.

MATERIAL AND METHODS

Retrospective study of 20 cases of childhood uveitis from 1995 to 2000. All patients received an ophthalmologic examination and an etiological search, with specific and/or symptomatic treatment and follow-up lasting from 6 months to 5 years.

RESULTS

The 20 children presenting uveitis were 4-16 years old, with etiologies as follows: 8 cases of Behçet's disease, 2 cases of Vogt-Koyanagi-Harada's disease, 1 case of sarcoidosis, 1 case of uveitis associated with coeliac disease, 1 case of toxoplasmosis, 1 case of sympathetic ophthalmia, 1 case of uveitis with streptococcal infection, 3 cases of ocular toxocarosis, and 2 cases with unknown etiology. Treatment based on the etiological findings was started in the cases of toxoplasmosis and uveitis from streptococcal infection. The others were treated with high- and then digressive-doses of corticosteroids.

ANALYSIS

We have noted the high incidence of Behçet's disease in our series. Progression was marked by frequent recurrence for one case of Vogt-Koyanagi-Harada's syndrome and one case of toxoplasmosis. This study also revealed a few cases of complicated cataract.

DISCUSSION

Clinical characteristics, diagnosis, and treatment of uveitis in children are discussed.

摘要

引言

儿童葡萄膜炎较为罕见,占所有病例的3%-8%。它需要与成人葡萄膜炎相同的诊断和病因学检查过程,但检查时会有额外困难,且病情有时进展隐匿。

材料与方法

对1995年至2000年期间20例儿童葡萄膜炎病例进行回顾性研究。所有患者均接受眼科检查和病因查找,并接受了特异性和/或对症治疗,随访时间为6个月至5年。

结果

20例患葡萄膜炎的儿童年龄在4至16岁之间,病因如下:贝赫切特病8例,伏格特-小柳-原田病2例,结节病1例,与乳糜泻相关的葡萄膜炎1例,弓形虫病1例,交感性眼炎1例,链球菌感染所致葡萄膜炎1例,眼弓蛔虫病3例,2例病因不明。针对弓形虫病和链球菌感染所致葡萄膜炎,根据病因检查结果进行治疗。其他病例则先给予高剂量然后递减剂量的皮质类固醇治疗。

分析

我们注意到在我们的病例系列中贝赫切特病的发病率较高。1例伏格特-小柳-原田综合征和1例弓形虫病的病情进展以频繁复发为特征。本研究还发现了几例复杂性白内障病例。

讨论

对儿童葡萄膜炎的临床特征、诊断和治疗进行了讨论。

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