Department of Ophthalmology and Visual Science, Tokyo Medical and Dental University Graduate School of Medical and Dental Sciences, Tokyo, Japan.
Ocul Immunol Inflamm. 2009 Sep-Oct;17(5):335-41. doi: 10.3109/09273940903137667.
To investigate a clinical survey of uveitis in southern Kyushu of Japan, where human T-lymphotropic virus type 1 (HTLV-1) and toxoplasmosis is highly endemic.
The clinical records of patients with uveitis between 1975 and 2007 at Miyata Eye Hospital were reviewed.
A total number of 1338 patients (2012 eyes), consisting of 526 men and 812 women with mean age of 50.5 years old, were analyzed. The most common clinical entity was HTLV-1 uveitis (17.1%), followed by Vogt-Koyanagi-Harada disease (9.9%), sarcoidosis (7.2%), toxoplasmosis (7.1%), Behçet's disease (4.3%) and others. Unclassified uveitis comprised 41.1% in the series. Anterior uveitis was seen in 30.8%, intermediate uveitis in 17.3%, posterior uveitis in 9.3%, and pan-uveitis in 42.6%.
HTLV-1 uveitis and toxoplasmosis were the major clinical entities in southern Kyushu of Japan. This relates to the high seroprevalence of the infectious agents in this region of Japan.
调查日本九州南部的葡萄膜炎临床研究,该地区人类 T 淋巴细胞病毒 1 型(HTLV-1)和弓形虫病呈高度地方性流行。
回顾 1975 年至 2007 年间在宫内眼科医院就诊的葡萄膜炎患者的临床记录。
共分析了 1338 例患者(2012 只眼),其中男性 526 例,女性 812 例,平均年龄为 50.5 岁。最常见的临床实体是 HTLV-1 葡萄膜炎(17.1%),其次是 Vogt-Koyanagi-Harada 病(9.9%)、结节病(7.2%)、弓形虫病(7.1%)、贝切特病(4.3%)和其他疾病。未分类的葡萄膜炎占该系列的 41.1%。前葡萄膜炎占 30.8%,中间葡萄膜炎占 17.3%,后葡萄膜炎占 9.3%,全葡萄膜炎占 42.6%。
HTLV-1 葡萄膜炎和弓形虫病是日本九州南部的主要临床实体。这与该地区感染因子的高血清流行率有关。