Olsson Gert E, Ahlm Clas, Elgh Fredrik, Verlemyr Ann-Christin, White Neil, Juto Per, Palo R Thomas
Department of Animal Ecology, Swedish University of Agricultural Sciences, SE-901 83 Umeå, Sweden.
J Wildl Dis. 2003 Apr;39(2):299-305. doi: 10.7589/0090-3558-39.2.299.
Puumala virus, genus Hantavirus, is the etiologic agent of nephropathia epidemica, a mild form of hemorrhagic fever with renal syndrome. The bank vole (Clethrionomys glareolus) is the natural reservoir species of this hantavirus. We initiated sampling of bank voles at sites of recently identified human nephropathia epidemica cases and paired control sites in the fall of 1995 in coastal areas of northern Sweden. Sites were trapped annually in spring and fall until 1999. Prevalence of antibody to Puumala virus was similar among local bank vole populations in the two types of sites over time. During peak years, however, the absolute number of bank voles was higher in case sites than control sites. Consequently, the likelihood of Puumala virus exposure was increased at case sites during population highs. This would imply that the risk of Puumala virus exposure to conspecifics and humans is habitat and site dependent with a temporal component.
普马拉病毒属于汉坦病毒属，是流行性肾病的病原体，流行性肾病是肾综合征出血热的一种轻症形式。棕背䶄（学名：Clethrionomys glareolus）是这种汉坦病毒的自然宿主物种。1995年秋季，我们在瑞典北部沿海地区最近确诊的流行性肾病病例地点以及配对的对照地点开始对棕背䶄进行采样。这些地点每年在春季和秋季设陷阱捕捉，直至1999年。随着时间推移，两种类型地点的当地棕背䶄种群中普马拉病毒抗体的流行率相似。然而，在高峰年份，病例地点的棕背䶄绝对数量高于对照地点。因此，在种群数量高峰期，病例地点接触普马拉病毒的可能性增加。这意味着接触普马拉病毒的风险对于同种个体和人类而言，与栖息地和地点有关，且具有时间因素。
