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[医院菌株标志物在医院感染发生情况研究中的应用]

[Use of markers of hospital strains in studying the occurrence of nosocomial infections].

作者信息

Srámová H, Dĕdicová D, Jedlicková Z, Kneiflová J, Lhotová H, Petrás P, Subertová V

机构信息

Státní zdravotní ústav, Praha.

出版信息

Cesk Epidemiol Mikrobiol Imunol. 1992 Dec;41(6):327-36.

PMID:1291111
Abstract

The submitted paper deals with one of the possible aspects of the investigation of nosocomial infections, i.e. investigations of the properties of hospital strains, their importance and possible use. The incidence of bacterial hospital strains was investigated in a surgical department of a district hospital of the North Bohemian region in October 1990; at the time of the survey 29 nosocomial infections (36.1%) were revealed by the prevalence method. Bacterial hospital strains were isolated from patients with a nosocomial infection, from the attending staff and the hospital environment. The following markers were investigated: biotyping, phagotyping, serotyping, toxin production, sensitivity to antimicrobial substances and sensitivity to disinfectants. Based on results of marking of hospital strains 7 incidences with a possible epidemiological association were detected where the hospital strain of equal or very similar properties dominated. The results of the investigation confirmed the important participation of the attending staff in the spread of nosocomial infections, in particular via contaminated hands, and drew attention to shortcomings as regards adherence to the hygienic and epidemiological regime in the investigated department.

摘要

提交的论文涉及医院感染调查的一个可能方面,即对医院菌株特性、其重要性及可能用途的研究。1990年10月,在北波希米亚地区一家区级医院的外科对细菌医院菌株的发生率进行了调查;在调查时,通过现患率法发现了29例医院感染(36.1%)。从医院感染患者、医护人员和医院环境中分离出细菌医院菌株。对以下指标进行了研究:生物分型、噬菌体型、血清分型、毒素产生、对抗菌物质的敏感性和对消毒剂的敏感性。根据医院菌株标记结果,检测到7起可能存在流行病学关联的事件,其中具有相同或非常相似特性的医院菌株占主导。调查结果证实了医护人员在医院感染传播中,特别是通过污染的手传播方面的重要作用,并提请注意被调查科室在遵守卫生和流行病学制度方面的不足之处。

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