Kneiflová J, Slosárek M, Melicherciková V, Paríková J
Státní zdravotní ústav, Praha.
Cesk Epidemiol Mikrobiol Imunol. 1992 Dec;41(6):355-61.
The authors tested the effect of a new disinfectant Lautericide produced by Qualichem Co. Neratovice which contains as the active agent acetate amine of coconut acid. For experiments standard methods were used and standard strains for testing of the following microbial strains: St. aureus, E. coli, Ps. aeruginosa, Proteus vulgaris, Serratia marcescens, Candida albicans, spores of Bacillus subtilis, M. tuberculosis, M. fortuitum, M. avium. As a model virus E. coli bacteriophage OX 174 was used. In concentrations from 0.04% to 0.5% and exposures from 2 to 10 minutes Lautercide exerted a bactericidal and fungicidal action. On spores of B. subtilis the preparation was ineffective even in a 10% concentration and 32-minute exposure. Devitalization of mycobacteria occurred after 15 min. action of Lautercide on M. tuberculosis and M. fortuitum, in M. avium in a 10% concentration in 60 min. Lautercide is ineffective against small resistant viruses without an integument. It is recommended to use Lautercide in a 1% aqueous solution for a one-stage disinfection combined with cleaning in the health services, veterinary medicine and in the field of communal hygiene. Before cleaning objects contaminated with infectious material, 5% Lautercide with 30 min. exposure is recommended. In disinfection of objects contaminated with mycobacteria it is recommended to use a 5% solution with 10-minute exposure for M. tuberculosis and M. fortuitum and a 10% solution for M. avium with 60-minute exposure.
作者测试了由夸利化学公司（位于内拉托维采）生产的新型消毒剂劳特杀菌剂的效果，该消毒剂的活性剂为椰油酸醋酸胺。实验采用标准方法，并使用标准菌株来测试以下微生物菌株：金黄色葡萄球菌、大肠杆菌、铜绿假单胞菌、普通变形杆菌、黏质沙雷氏菌、白色念珠菌、枯草芽孢杆菌孢子、结核分枝杆菌、偶然分枝杆菌、鸟分枝杆菌。以大肠杆菌噬菌体OX 174作为模型病毒。劳特杀菌剂在浓度为0.04%至0.5%、作用时间为2至10分钟时具有杀菌和杀真菌作用。对于枯草芽孢杆菌孢子，即使在10%的浓度和32分钟的作用时间下，该制剂也无效。劳特杀菌剂作用于结核分枝杆菌和偶然分枝杆菌15分钟后，分枝杆菌失活；在浓度为10%时，作用于鸟分枝杆菌60分钟后失活。劳特杀菌剂对无包膜的小型抗性病毒无效。建议在医疗卫生服务、兽医学和公共卫生领域，将1%的劳特杀菌剂水溶液用于与清洁相结合的一级消毒。在清洁被传染性物质污染的物体之前，建议使用5%的劳特杀菌剂，作用30分钟。在对被分枝杆菌污染的物体进行消毒时，建议对结核分枝杆菌和偶然分枝杆菌使用5%的溶液，作用10分钟；对鸟分枝杆菌使用10%的溶液，作用60分钟。
