Khodadoust Ali, Quinter Ania Porazinski
Connecticut Eyecare Center, New Haven, CT 06519, USA.
Arch Ophthalmol. 2003 Aug;121(8):1189-93. doi: 10.1001/archopht.121.8.1189.
To describe a microsurgical approach to a selective pedunculated conjunctival flap for the treatment of chronic corneal ulceration with or without corneal perforation, and to present the results of 50 consecutive cases.
Retrospective, noncomparative case series and case reports. Patients All patients who had microsurgical conjunctival flap procedures for the treatment of chronic corneal ulcers between 1982 and 1996 at the Connecticut Eyecare Center, New Haven.
Partial pedunculated conjunctival flap surgery.
Review of the initial ocular diagnoses and characteristics as well as retrospective study of the postoperative course.
Resolution of the corneal ulcer and postoperative stability of the conjunctival flap.
Sixty-two percent of the corneal ulcers treated were nonperforated, and 38% were perforated. The diagnoses included herpes simplex virus (14 patients), bacterial ulcer (11 patients), rheumatoid arthritis (8 patients), aphakic bullous keratopathy (6 patients), graft rejection (4 patients), herpes zoster virus (5 patients), and other (2 patients). Postoperatively, 94% of the conjunctival flaps were stable, and 3% had failed. The procedures were definitive in 64% of cases and temporary in 36%; 61% of patients received a corneal transplant 6 to 24 months postoperatively, and in 38% the flaps were removed 6 to 12 months after the original lesion had healed.
A selective pedunculated conjunctival flap is an effective and practical surgical approach to the treatment of perforated and nonperforated corneal ulcers that have not responded to other types of medical therapy.
描述一种用于治疗伴有或不伴有角膜穿孔的慢性角膜溃疡的选择性带蒂结膜瓣显微手术方法,并展示连续50例病例的结果。
回顾性、非对照病例系列和病例报告。患者为1982年至1996年期间在纽黑文康涅狄格眼保健中心接受显微结膜瓣手术治疗慢性角膜溃疡的所有患者。
部分带蒂结膜瓣手术。
回顾初始眼部诊断和特征以及对术后病程进行回顾性研究。
角膜溃疡的愈合以及结膜瓣术后的稳定性。
所治疗的角膜溃疡中62%未穿孔,38%穿孔。诊断包括单纯疱疹病毒(14例患者)、细菌性溃疡(11例患者)、类风湿性关节炎(8例患者)、无晶状体大泡性角膜病变(6例患者)、移植排斥反应(4例患者)、带状疱疹病毒(5例患者)以及其他(2例患者)。术后,94%的结膜瓣稳定,3%失败。该手术在64%的病例中为确定性手术,36%为临时性手术;61%的患者在术后6至24个月接受了角膜移植,38%的患者在原病变愈合后6至12个月移除了结膜瓣。
选择性带蒂结膜瓣是治疗对其他类型药物治疗无反应的穿孔和未穿孔角膜溃疡的一种有效且实用的手术方法。