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改良结膜移植治疗角膜溃疡

Improved conjunctival transplantation for corneal ulcer.

作者信息

Zhou Qinghua, Long Xianhua, Zhu Xiaohua

机构信息

Department of Ophthalmology, Second Xiangya Hospital, Central South University, Changsha 410008, China.

出版信息

Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2010 Aug;35(8):814-8. doi: 10.3969/j.issn.1672-7347.2010.08.007.

Abstract

OBJECTIVE

To evaluate the therapeutic effect of pedical conjunctival flap transposition on refractory corneal ulcer.

METHODS

The data of 56 eyes of 56 patients with refractory corneal ulcer who underwent pedical conjuctival transposition in a tertiary eye unit in China from June 2005 to June 2009 were retrospectively analyzed. There were 36 infective corneal ulcers, 9 keratoplasty graft ulcers, 4 traumatic ulcers, and 7 chemical burn ulcers. All patients were treated with focal debridement and pedical conjuctival flap transposition.

RESULTS

Forty-seven out of 56 (83.9%) were cured after one surgery, and 5 (8.9%) had conjunctival flap retraction, among which 3 underwent the second surgery and 2 had the third surgery to completely heal. Four patients (7.2%) turned to lamellar keratoplasty because of fungal corneal ulcer relapse. Ulcer in 52 patients healed and the globe preserved. They had different levels of vision improvement.

CONCLUSION

Pedical conjunctival flap transposition is effective for refractory corneal ulcer.

摘要

目的

评估带蒂结膜瓣转位术治疗难治性角膜溃疡的疗效。

方法

回顾性分析2005年6月至2009年6月在中国一家三级眼科单位接受带蒂结膜转位术的56例难治性角膜溃疡患者的56只眼的数据。其中感染性角膜溃疡36例,角膜移植术后植片溃疡9例,外伤性溃疡4例,化学性烧伤溃疡7例。所有患者均接受病灶清创及带蒂结膜瓣转位术治疗。

结果

56例患者中,47例(83.9%)一次手术后治愈,5例(8.9%)结膜瓣回缩,其中3例行二次手术,2例行三次手术完全愈合。4例(7.2%)因真菌性角膜溃疡复发改行板层角膜移植术。52例患者溃疡愈合,眼球保留。视力有不同程度提高。

结论

带蒂结膜瓣转位术治疗难治性角膜溃疡有效。

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