tRNA synthetase paralogs: evolutionary links in the transition from tRNA-dependent amino acid biosynthesis to de novo biosynthesis.
作者信息
Francklyn Christopher
机构信息
Department of Biochemistry, University of Vermont Health Sciences Complex, Burlington, VT 05405, USA.
出版信息
Proc Natl Acad Sci U S A. 2003 Aug 19;100(17):9650-2. doi: 10.1073/pnas.1934245100. Epub 2003 Aug 11.
Abstract
摘要
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On protein synthesis.论蛋白质合成。
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When contemporary aminoacyl-tRNA synthetases invent their cognate amino acid metabolism.当当代氨酰-tRNA合成酶发明它们同源的氨基酸代谢时。
Proc Natl Acad Sci U S A. 2003 Aug 19;100(17):9837-42. doi: 10.1073/pnas.1632156100. Epub 2003 Jul 21.
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Aminoacyl-tRNA synthesis: a postgenomic perspective.氨酰-tRNA合成：后基因组时代的视角
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An integrated analysis of the genome of the hyperthermophilic archaeon Pyrococcus abyssi.嗜热古菌深渊热球菌基因组的综合分析。
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Selection of tRNA by the ribosome requires a transition from an open to a closed form.核糖体对tRNA的选择需要从开放形式转变为封闭形式。
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Thiamine derivatives bind messenger RNAs directly to regulate bacterial gene expression.硫胺素衍生物直接结合信使核糖核酸以调控细菌基因表达。
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Pyrrolysine encoded by UAG in Archaea: charging of a UAG-decoding specialized tRNA.古菌中由UAG编码的吡咯赖氨酸：对解码UAG的特殊tRNA进行氨酰化
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Transfer RNA-dependent amino acid biosynthesis: an essential route to asparagine formation.依赖转运RNA的氨基酸生物合成：天冬酰胺形成的一条重要途径。
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V-shaped structure of glutamyl-tRNA reductase, the first enzyme of tRNA-dependent tetrapyrrole biosynthesis.谷氨酰 - tRNA还原酶的V形结构，tRNA依赖性四吡咯生物合成的首个酶。
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Uniform binding of aminoacyl-tRNAs to elongation factor Tu by thermodynamic compensation.通过热力学补偿实现氨酰-tRNA与延伸因子Tu的均匀结合。
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