Varani E, Pirazzini L, Casanova R, Patroncini A, Maresta A
Servizio di Cardiologia, Ospedale per Gli infermi, Faenza.
G Ital Cardiol. 1992 Sep;22(9):1069-75.
The aim of this prospective study was to assess the prognostic and most suitable management of AMI in elderly patients (age > or = 75 years). From September 1988 to August 1991, 129 such patients (pts) were evaluated: 35 (27%) were admitted to CCU because of arrhythmias or severe hemodynamic complications; 94 (73%) were addressed, according to bed availability, to CCU (55 pts) or Cardiology Ward (39 pts), where all patients underwent continuous ECG monitoring for at least 72 hours. Age, gender, history of previous angina or myocardial infarction, presence of chest pain or ECG ischemia on admission, site and extent of AMI, delay on admission, CPK-MB peak, recurrent angina, arrhythmias, heart failure, emotional disorders, hospital mortality and length of hospital stay were compared. Our results show that elderly patients who suffered from complicated AMI were at high risk for death and severe in-hospital complications. No significant prognostic differences were observed between the two groups with uncomplicated AMI. Thus hospitalization in the Cardiology Ward seems to be valuable, safe and well tolerated in our population of elderly patients with AMI, and without initial complications.
这项前瞻性研究的目的是评估老年患者(年龄≥75岁)急性心肌梗死(AMI)的预后及最合适的治疗方法。1988年9月至1991年8月,对129例此类患者进行了评估:35例(27%)因心律失常或严重血流动力学并发症入住冠心病监护病房(CCU);根据床位情况,94例(73%)患者入住CCU(55例)或心内科病房(39例),所有患者均接受至少72小时的连续心电图监测。比较了患者的年龄、性别、既往心绞痛或心肌梗死病史、入院时胸痛或心电图缺血情况、AMI的部位和范围、入院延迟时间、肌酸磷酸激酶同工酶(CPK-MB)峰值、复发性心绞痛、心律失常、心力衰竭、情绪障碍、住院死亡率及住院时间。我们的结果表明,患有复杂AMI的老年患者死亡和严重院内并发症风险较高。两组无并发症的AMI患者之间未观察到显著的预后差异。因此,在心内科病房住院对我们患有AMI且无初始并发症的老年患者群体而言似乎是有价值、安全且耐受性良好的。