Nath G, Singh S P, Sanyal S C
Department of Microbiology, Banaras Hindu University, Varanasi.
Indian J Med Res. 1992 Nov;95:259-62.
The etiologic role of rotavirus in acute diarrhoeal illness in children under five years of age was studied over a period of one year in an urban slum community. Rotavirus was detected in 17.7 per cent of 376 children with diarrhoea and 4 per cent of 299 healthy children with maximum prevalence at 19-24 months of age with statistically comparable detection in 0-6 months of age. The overall prevalence was significantly higher in children below 2 yr as compared to those between 2-5 yr of age. Girls (24.1%) were more susceptible amongst the diarrhoeal group in comparison to boys (13.8%). Diarrhoea due to rotavirus was more prevalent during the cooler months (November-February) of the year and no correlation was observed with rainfall and relative humidity. Rotavirus as the sole pathogen was observed in 9 per cent children with diarrhoea and in the rest, association of Cryptosporidium (3%) was observed for the first time with this virus along with other known enteropathogenic bacteria and parasites, enterotoxigenic Escherichia coli being the commonest organism.
在一个城市贫民窟社区，对轮状病毒在5岁以下儿童急性腹泻疾病中的病因学作用进行了为期一年的研究。在376名腹泻儿童中，17.7%检测出轮状病毒；在299名健康儿童中，4%检测出轮状病毒，最高患病率出现在19至24个月龄，0至6个月龄的检测率在统计学上与之相当。2岁以下儿童的总体患病率明显高于2至5岁的儿童。腹泻组中女孩（24.1%）比男孩（13.8%）更易感染。轮状病毒引起的腹泻在一年中较凉爽的月份（11月至2月）更为普遍，且未观察到与降雨量和相对湿度的相关性。9%的腹泻儿童中轮状病毒为唯一病原体，其余儿童中，首次观察到隐孢子虫（3%）与该病毒以及其他已知的肠道致病细菌和寄生虫有关联，产肠毒素大肠杆菌是最常见的病原体。
