Soudamini K K, Unnikrishnan M C, Soni K B, Kuttan R
Amala Cancer Research Centre, Amala Nagar, Trichur.
Indian J Physiol Pharmacol. 1992 Oct;36(4):239-43.
Effect of oral administration of curcumin (diferuloyl methane) on lipid peroxidation in various organs of mice like liver, lung, kidney and brain was studied in control animals as well as those given carbon tetrachloride, paraquat and cyclophosphamide. Oral administration of curcumin significantly lowered the increased peroxidation of lipids in these tissues produced by these chemicals. Administration of curcumin was also found to lower significantly the serum and tissue cholesterol levels in these animals, indicating that the use of curcumin helps in conditions associated with peroxide induced injury such as liver damage and arterial diseases.
在对照动物以及给予四氯化碳、百草枯和环磷酰胺的动物中，研究了口服姜黄素（二阿魏酰甲烷）对小鼠肝脏、肺、肾脏和大脑等各种器官脂质过氧化的影响。口服姜黄素显著降低了这些化学物质在这些组织中引起的脂质过氧化增加。还发现给予姜黄素可显著降低这些动物的血清和组织胆固醇水平，这表明使用姜黄素有助于改善与过氧化物诱导损伤相关的病症，如肝损伤和动脉疾病。
