Mascarenhas J F, Borker A S, Venkatesh P
Department of Physiology, Goa Medical College.
Indian J Physiol Pharmacol. 1992 Oct;36(4):244-6.
The effects of estrogen (OVX-EB) and progesterone (OVX-P) administration to ovariectomized (OVX) rats on food and fluid intakes were studied in fifty five animals grouped into three series. Animals in each series were given a choice of two fluids viz. tap water and either 5% glucose (5 G/W) or 12% glucose (12 G/W) or 1.5% Sodium chloride (S/W) by two bottle preference. Both hormones had a differential effect on the ingestion of the two concentrations of glucose while progesterone markedly increased the intake of Sodium Chloride. Could the putative role of the ovarian hormones be hedonic for glucose and homeostatic for salt?
在五十五只大鼠中开展了研究，这些大鼠被卵巢切除（OVX），并被分为三个组，研究了对其给予雌激素（OVX-EB）和孕激素（OVX-P）后对食物和液体摄入量的影响。每个组的动物可通过双瓶偏好法在两种液体中进行选择，即自来水和5%葡萄糖（5 G/W）或12%葡萄糖（12 G/W）或1.5%氯化钠（S/W）。两种激素对两种浓度葡萄糖的摄取有不同影响，而孕激素显著增加了氯化钠的摄入量。卵巢激素的假定作用会不会是对葡萄糖产生享乐性影响而对盐产生稳态影响呢？
