Brodie Martin J, French Jacqueline A
Epilepsy Unit, Division of Cardiovascular and Medical Sciences, Western Infirmary, Glasgow, Scotland, United Kingdom.
Epileptic Disord. 2003 May;5 Suppl 1:S65-72.
Physicians treating patients with epilepsy have a host of thera-peutic options. Drug choice is dictated first by the seizure(s) and/or epilepsy syndrome. Age is also a factor. Special considerations apply to women, particu-larly during their childbearing years, and to patients who are learning-disabled. Drug selection is further influenced by such characteristics as spectrum of activity, rapid response, low potential for drug-drug interactions, and ease of use. In addition to clinical trial data, postmarketing assessments of the new antiepileptic drugs provide useful clinical information on efficacy and safety. Levetiracetam has specific characteristics that make it an optimal choice for many patient populations.
治疗癫痫患者的医生有许多治疗选择。药物选择首先取决于癫痫发作和/或癫痫综合征。年龄也是一个因素。对于女性，尤其是在育龄期，以及有学习障碍的患者，有特殊的考虑因素。药物选择还会受到活性谱、快速反应、药物相互作用可能性低和使用方便等特性的影响。除了临床试验数据外，新型抗癫痫药物的上市后评估也提供了关于疗效和安全性的有用临床信息。左乙拉西坦具有特定的特性，使其成为许多患者群体的最佳选择。
