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在传染性单核细胞增多症患者样本中对健康相关生产力调查问卷日记(HRPQ-D)进行验证:一项1期多中心临床试验的结果。

Validation of the Health-Related Productivity Questionnaire Diary (HRPQ-D) on a sample of patients with infectious mononucleosis: results from a phase 1 multicenter clinical trial.

作者信息

Kumar Ritesh N, Hass Steven L, Li Jim Zhiming, Nickens Dana J, Daenzer Carolyn L, Wathen Lynne K

机构信息

College of Pharmacy, University of Michigan, Ann Arbor, Michigan, USA.

出版信息

J Occup Environ Med. 2003 Aug;45(8):899-907. doi: 10.1097/01.jom.0000083039.56116.79.

DOI:10.1097/01.jom.0000083039.56116.79
PMID:12915792
Abstract

The objective of this work was to assess the performance of the newly developed Health-Related Productivity Questionniare-Diary (HRPQ-D). Patients completed the HRPQ-D daily for 1-week periods during weeks 1, 2, 4, and 8 of a clinical trial for infectious mononucleosis. Productivity data were collected on a daily basis in terms of absenteeism, presenteeism, and combined lost productivity for three work venues (work outside home, housework, and classes/homework). These were then correlated with patient symptom scores. Symptom scores were positively correlated with lost work hours because of absenteeism and combined lost productivity scores. However, negative correlations were observed between symptom scores and the lost work hours due to presenteeism. The HRPQ-D demonstrated good construct validity, making it a useful tool for determining productivity levels across different work venues within clinical trial or survey research applications.

摘要

这项工作的目的是评估新开发的健康相关生产力问卷-日记(HRPQ-D)的性能。在传染性单核细胞增多症的一项临床试验的第1、2、4和8周期间,患者连续1周每天填写HRPQ-D。每天收集三个工作场所(外出工作、家务和课程/家庭作业)的旷工、出勤不足和综合生产力损失方面的生产力数据。然后将这些数据与患者症状评分相关联。症状评分与旷工导致的工作时间损失和综合生产力损失评分呈正相关。然而,症状评分与出勤不足导致的工作时间损失之间存在负相关。HRPQ-D显示出良好的结构效度,使其成为在临床试验或调查研究应用中确定不同工作场所生产力水平的有用工具。

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