Liu Feng, Zhou Shuimiao, Li Zhaoji, Zhang Suqin, Xu Yue
Department of Otolaryngology, Changhai Hospital, Second Military Medical University, Shanghai 200433.
Lin Chuang Er Bi Yan Hou Ke Za Zhi. 2003 May;17(5):291-3.
To investigate how to induce experimental maxillary sinusitis so as to explore its bacteriologic changes.
Forty New Zealand white rabbits were divided into six groups according to different methods to create experimental sinusitis. The purulent discharge of sinus and bacteria culture is investigated in different times.
The positive rate of bacteria culture are 0%(control group), 20%(sham-operation group), 84.6% (ostia-block group), 10%(bacteria inoculation group) and 100%(ostia-block plus bacteria inoculation group). The cultivate bacteria are mainly inoculate ones when sinusitis induced shorter than 2 weeks. If maxillary sinusitis induced more than 3 weeks, the cultivate bacteria are mainly opportunistic pathogens of rabbits.
Experimental maxillary sinusitis can be successfully induced by bacteria inoculation with an ostium closed. The cultivate rate of opportunistic bacteria is related to the process of sinusitis.
探讨如何诱导实验性上颌窦炎，以探索其细菌学变化。
将40只新西兰白兔按不同方法分为六组以建立实验性鼻窦炎。在不同时间对鼻窦脓性分泌物进行调查及细菌培养。
细菌培养阳性率分别为0%（对照组）、20%（假手术组）、84.6%（窦口阻塞组）、10%（细菌接种组）和100%（窦口阻塞加细菌接种组）。当鼻窦炎诱发时间短于2周时，培养出的细菌主要为接种菌。如果上颌窦炎诱发超过3周，培养出的细菌主要为家兔的机会致病菌。
通过封闭窦口并接种细菌可成功诱导实验性上颌窦炎。机会性细菌的培养率与鼻窦炎的病程有关。
