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兔鼻窦炎后上颌窦副口的形成

Development of maxillary accessory ostium following sinusitis in rabbits.

作者信息

Genc Selahattin, Ozcan Muge, Titiz Ali, Unal Adnan

机构信息

Kecioren Education and Research Hospital ENT Clinic, Ankara, Turkey.

出版信息

Rhinology. 2008 Jun;46(2):121-4.

Abstract

OBJECTIVES/HYPOTHESIS: Maxillary accessory ostium is one of the anatomical variations that may play a role in the development of chronic maxillary sinusitis. Although some authors claim that accessory ostia develop following acute maxillary sinusitis, it is not clear whether they are congenital or acquired.

STUDY DESIGN

Animal experimental study.

METHODS

Ten New Zealand type rabbits were used in the study. In phase 1, lateral nasal walls of five New Zealand type rabbits were examined for the presence of natural and accessory ostia of the maxillary sinus and any area resembling fontanelles in humans. In phase 2, experimental sinusitis was induced in the right sides of the other five rabbits. Following sacrifice, lateral nasal walls were examined for the development of accessory ostia.

RESULTS

Six of the ten sides of phase 1 animals contained a membranous part in the medial wall of the maxillary sinus resembling the fontanelles in humans (60%). None of them had an accessory maxillary ostium. Accessory ostia developed in two of the five sides with sinusitis (40%).

CONCLUSIONS

We have shown for the first time that accessory maxillary ostia develop following experimental sinusitis in rabbits. Further studies in humans are indicated.

摘要

目的/假设:上颌窦副口是一种解剖变异,可能在慢性上颌窦炎的发生发展中起作用。尽管一些作者声称副口是在急性上颌窦炎后形成的,但它们是先天性的还是后天获得的尚不清楚。

研究设计

动物实验研究。

方法

本研究使用了10只新西兰兔。在第一阶段,检查了5只新西兰兔的鼻外侧壁,以确定上颌窦自然口和副口的存在以及任何类似人类囟门的区域。在第二阶段,对另外5只兔的右侧诱发实验性鼻窦炎。处死后,检查鼻外侧壁副口的形成情况。

结果

第一阶段动物的10个侧面中有6个在上颌窦内侧壁含有类似人类囟门的膜性部分(60%)。它们均无上颌窦副口。在5个患有鼻窦炎的侧面中有2个出现了副口(40%)。

结论

我们首次证明了兔实验性鼻窦炎后会出现上颌窦副口。有必要在人类中进行进一步研究。

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