Liu Feng, Zhou Shuimiao, Zhang Suqin, Xu Yue
Department of Otolaryngology, Changhai Hospital, the Second Military Medical University, Shanghai, 200433, China.
Lin Chuang Er Bi Yan Hou Ke Za Zhi. 2005 Mar;19(5):216-8.
To investigate mucosal pathologic and ultrastructure changes relate to experimental maxillary sinusitis process in rabbits. The demarcation of acute and chronic maxillary sinusitis will be determined according to pathologic effects.
Thirty New Zealand white rabbits have been induced sinusitis will be divided into different groups according to the time of process. The pathologic changes are observed by microscope, scanning electric microscope and transmission electric microscope.
Within 3 weeks to induce infection the inflammation mainly show in acute style while after 3 weeks the main manifestation are chronic changes. In epithelium layer cilia shedding increased, the number of goblet cell added, squamous epithelium metaplasia and epithelia necrosis were observed during inflammatory process. In lamina propria glands metaplasia and decreased, the fibrosis is densed.
The pathologic changes of maxillary mucosa are related to process. The borderline of acute and chronic experimental maxillary sinusitis is 3 weeks.
研究兔实验性上颌窦炎过程中黏膜的病理及超微结构变化。根据病理效应确定急性和慢性上颌窦炎的分界。
将30只诱导出鼻窦炎的新西兰白兔根据病程时间分为不同组。通过显微镜、扫描电镜和透射电镜观察病理变化。
感染诱导后3周内炎症主要表现为急性，3周后主要表现为慢性改变。炎症过程中可见上皮层纤毛脱落增加、杯状细胞数量增多、鳞状上皮化生及上皮坏死。固有层腺体化生及减少，纤维化致密。
上颌黏膜的病理变化与病程有关。实验性急性和慢性上颌窦炎的界限为3周。
