Martini M, Drigo M, Dalla Pozza M, Ferrari G, Martinello F, Sona B
Dipartimento di Sanità Pubblica, Patologia Comparata e Igiene Veterinaria, Università di Padova, Agripolis, Italy.
J Vet Med B Infect Dis Vet Public Health. 2003 May;50(4):191-5. doi: 10.1046/j.1439-0450.2003.00656.x.
A 3-year study (1997-2000) was performed on 294 swine herds from Italy, where a National Programme of Control of Aujeszky's Disease (AD) based on compulsory vaccination has been operative since 1997. Aim of the study was to evaluate the progress of this control programme using a survival approach applied to gE-seropositive herds at the beginning of the programme. The cumulative proportion of herds still gE-seropositive at the end of the study was 0.57. No significant difference in the probability of becoming gE-seronegative during the study period was found between herds of different type (breeding versus farrow-to-finish) whereas significant differences were seen between herds from different areas. The Cox's proportional hazards regression, performed on data from 79 herds, showed that the only risk factor significantly associated with a higher probability of becoming gE-seronegative is again the geographical location. Other risk factors considered in the analysis were: type of enterprise, type of replacement of animals, herd size, pig and pig herds densities around the farm, distance from the nearest pig herd and year of beginning of the vaccination with a gE-deleted vaccine.
对来自意大利的294个猪群进行了一项为期3年的研究（1997 - 2000年），自1997年起，意大利实施了一项基于强制疫苗接种的奥耶斯基氏病（AD）国家控制计划。该研究的目的是使用一种生存分析方法来评估这个控制计划的进展情况，该方法应用于计划开始时gE血清学阳性的猪群。研究结束时仍为gE血清学阳性的猪群累积比例为0.57。在研究期间，不同类型（繁殖型与从产仔到育肥型）的猪群之间，转为gE血清学阴性的概率没有显著差异，而不同地区的猪群之间则存在显著差异。对79个猪群的数据进行的Cox比例风险回归分析表明，与转为gE血清学阴性的较高概率显著相关的唯一风险因素仍是地理位置。分析中考虑的其他风险因素包括：企业类型、动物替换类型、猪群规模、猪场周围的猪和猪群密度、与最近猪群的距离以及开始接种gE缺失疫苗的年份。
