Fransen M, McConnell S, Bell M
Musculo-skeletal Injuries, Institute for International Health, 144 Burren Street, Newtown, NSW, Australia.
Cochrane Database Syst Rev. 2003(3):CD004286. doi: 10.1002/14651858.CD004286.
Biomechanical factors, such as reduced muscle strength and joint mal-alignment, have an important role in the initiation and progression of osteoarthritis (OA) of the hip or knee. Currently, there is no known cure for OA, however, disease-related factors, such as impaired muscle function and reduced fitness, are potentially amenable to therapeutic exercise.
To determine whether land-based therapeutic exercise is beneficial for people with OA of the hip or knee in terms of reduced joint pain, improved physical function and/or the patient's global assessment of therapeutic effectiveness.
Five databases (the Cochrane Controlled Trials Register, the Cochrane Musculoskeletal Group Trials Register, MEDLINE, CINAHL, PEDro) were searched up until November 2002.
All randomized controlled trials comparing some form of land-based therapeutic exercise (as opposed to exercises conducted in the water) with a non-exercise group.
Two reviewers independently extracted data and assessed methodological quality. All analyses were conducted on continuous outcomes.
Only 2 studies totaling about 100 participants, could potentially provide data on people with OA of the hip. However, for OA of the knee, 17 included studies provided data on 2562 participants. For pain, combining the results revealed a beneficial treatment effect (standardised mean difference) of.39 (95% confidence interval (CI).30 -.47) while for self-reported physical function a beneficial treatment effect of.31 (95% CI.23 -.39). Group format programs appeared to be as effective as treatments provided on a one-to-one basis. The results were sensitive to various aspects of study design methodology.
REVIEWER'S CONCLUSIONS: Land-based therapeutic exercise was shown to reduce pain and improve physical function for people with OA of the knee. There were insufficient data to provide useful guidelines on optimal exercise type or dosage. Supervised exercise classes appeared to be as beneficial as treatments provided on a one-to-one basis.
生物力学因素,如肌肉力量减弱和关节排列不齐,在髋部或膝部骨关节炎(OA)的发病和进展中起重要作用。目前,OA尚无已知的治愈方法,然而,与疾病相关的因素,如肌肉功能受损和体能下降,可能适合进行治疗性运动。
确定陆地治疗性运动对于髋部或膝部OA患者在减轻关节疼痛、改善身体功能和/或患者对治疗效果的总体评估方面是否有益。
检索了五个数据库(Cochrane对照试验注册库、Cochrane肌肉骨骼组试验注册库、MEDLINE、CINAHL、PEDro),截至2002年11月。
所有比较某种形式的陆地治疗性运动(与水中运动相对)与非运动组的随机对照试验。
两名评价者独立提取数据并评估方法学质量。所有分析均基于连续结果进行。
仅有2项研究,共约100名参与者,可能提供有关髋部OA患者的数据。然而,对于膝部OA,纳入的17项研究提供了2562名参与者的数据。对于疼痛,综合结果显示有益的治疗效果(标准化均数差)为0.39(95%置信区间(CI)0.30 - 0.47),而对于自我报告的身体功能有益的治疗效果为0.31(95% CI 0.23 - 0.39)。团体形式的项目似乎与一对一提供的治疗效果相同。结果对研究设计方法的各个方面敏感。
陆地治疗性运动被证明可减轻膝部OA患者疼痛并改善身体功能。数据不足,无法提供关于最佳运动类型或剂量的有用指南。有监督的运动课程似乎与一对一提供的治疗同样有益。