Chen Xuan, Jin Mei
Department of Neurology, Nanfang Hospital, First Military Medical University, Guangzhou 510515, China.
Di Yi Jun Yi Da Xue Xue Bao. 2003 Aug;23(8):812-5.
To investigate of changes in N400 event-related potentials (ERPs) in recognition of semantically matching ending words of Chinese sentences for analysis of the characteristics of Chinese sentence N400 in healthy subjects.
Fifteen healthy right-handed volunteers aging from 21 to 36 years old were tested for N400 when they were asked to read Chinese sentences with semantically matching or mismatching ending words.
Significant differences were found in N400 latencies and amplitudes when the subjects were reading the carefully designed Chinese sentences (P<0.05). The latencies of N400 were delayed and the amplitudes increased when the subjects were confronted with mismatching ending words, in the event of which N400 amplitudes were higher in the left than in the right hemisphere of the brain.
N400 in Chinese sentence-ending word matching test is close by related to the semantic context of the word recognition, and possesses clinically valuable recognition potential for assessing language disorders.
研究健康受试者在识别汉语句子语义匹配结尾词时N400事件相关电位（ERP）的变化，以分析汉语句子N400的特征。
对15名年龄在21至36岁之间的健康右利手志愿者进行测试，要求他们阅读结尾词语义匹配或不匹配的汉语句子，并记录N400。
当受试者阅读精心设计的汉语句子时，N400潜伏期和波幅存在显著差异（P<0.05）。当面对不匹配的结尾词时，N400潜伏期延迟，波幅增大，且此时大脑左半球的N400波幅高于右半球。
汉语句子结尾词匹配测试中的N400与词识别的语义背景密切相关，对评估语言障碍具有临床价值的识别潜力。
