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四倍体图谱:同源四倍体物种连锁图谱的构建

TetraploidMap: construction of a linkage map in autotetraploid species.

作者信息

Hackett C A, Luo Z W

机构信息

Biomathematics and Statistics Scotland, Scottish Crop Research Institute, Invergowrie, Dundee DD2 5DE, UK.

出版信息

J Hered. 2003 Jul-Aug;94(4):358-9. doi: 10.1093/jhered/esg066.

DOI:10.1093/jhered/esg066
PMID:12920109
Abstract

TetraploidMap is a suite of Fortran 90 routines run from Microsoft Windows with a text-based input and output. TetraploidMap enables the user to assemble a linkage map from dominant and codominant (multiallelic) marker loci scored for the parents and full-sib progeny of a cross in an autotetraploid species. It includes routines for the inference of the parental genotypes, identification of linkage groups, two-point analysis to estimate the recombination frequency and LOD score between all pairs of marker in a linkage group, and locus ordering by simulated annealing.

摘要

TetraploidMap是一组用Fortran 90编写的程序,可在Microsoft Windows系统上运行,采用基于文本的输入和输出方式。TetraploidMap能让用户根据某同源四倍体物种杂交的亲本及全同胞后代所测定的显性和共显性(多等位基因)标记位点来构建连锁图谱。它包括用于推断亲本基因型、识别连锁群、两点分析以估计连锁群中所有标记对之间的重组频率和LOD分数,以及通过模拟退火进行基因座排序的程序。

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