Ayaki Masahiko, Ishida Yoshiko, Nishimura Eiichi, Yaguchi Shigeo
Department of Ophthalmology, Fujigaoka Hospital, Showa University School of Medicine, Yokohama, Japan.
Ophthalmic Res. 2003 Sep-Oct;35(5):261-7. doi: 10.1159/000072147.
To compare lens epithelial cell migration between intraocular lens (IOL) optics and the posterior capsule of IOLs with various edges and haptic angulations.
Experimental acrylic IOLs with 3 types of finishing (none, polishing, tumbling and polishing) and 2 types of haptic angulation (10 and 15 degrees ) as well as 3 (AcrySof MA30BA, Sensar AR40, CeeOn 911) clinically implanted IOLs were inserted in rabbit eyes. Scanning electron-microscopic examination of IOLs was carried out before surgery and histological examination of lens capsules 3 weeks after surgery. The grading of lens epithelial cell migration under the IOL was made by scoring.
Scanning electron-microscopic examination showed that the optic edge sharpness decreased according to the finishing in experimental IOLs. The AcrySof and CeeOn lenses had sharp edges and the Sensar had a rounded edge. The migration score was highest in the IOL with a rounded edge whereas it was lowest in IOLs with a sharp edge and large haptic angulation. There was no significant difference between the scores of clinically implanted IOLs.
Sharpness of the optic edge may be a critical factor for the prevention of posterior capsule opacification and more important than haptic angulation in acrylic IOLs.
