Ee Hock-Leong, Yosipovitch Gil
National Skin Center, Singapore, Republic of Singapore.
Dermatology. 2003;207(2):196-8. doi: 10.1159/000071795.
Taxanes are a new group of chemotherapeutic agents, which share some pharmacological characteristics with methotrexate. Methotrexate has previously been reported to cause a photo recall phenomenon which develops 3-5 days after UV radiation, suggesting that taxanes can induce a similar reaction. This should be added to the list of cutaneous side-effects of this class of chemotherapeutic agents. We report a case of photo recall phenomenon in a 55-year-old Chinese woman with metastatic breast cancer who was undergoing chemotherapy with taxanes.
紫杉烷类是一类新型化疗药物,它们与甲氨蝶呤具有一些药理学特性。此前有报道称甲氨蝶呤会引起光回忆现象,该现象在紫外线辐射后3至5天出现,这表明紫杉烷类可能会引发类似反应。这应被列入此类化疗药物的皮肤副作用清单中。我们报告了一例55岁患有转移性乳腺癌且正在接受紫杉烷类化疗的中国女性出现光回忆现象的病例。