Navrátil S, Knotek Z, Manásková M, Martínek J, Stefan M, Soukup T, Soukupová I
Výzkumný ústav veterinárniho lékarství, Brno.
Vet Med (Praha). 1992 Sep-Oct;37(9-10):509-16.
Cloprostenol, a prostaglandin F2-alpha analogue, used in the Czechoslovak preparation Oestrophan ing. Spofa was tested by a new nontraditional use. The effect of cloprostenol use on reproductive parameters of sows after piglet weaning was followed in a set of 456 experimental and 434 control sows. The effect of single intramuscular instillation of cloprostenol was tested in five partial observations: to multiparous sows at a dose of 175 micrograms on the day of weaning (experimental group no. 1), on day 1 after weaning (group no. 2), 500 micrograms on day 1 after weaning (group no.3), to primiparous sows at a dose of 500 microgram on day 1 after weaning (group no. 4). The treatment used in group no. 4 was also applied to 42 primiparous sows kept on a farm with regular occurrence of post-weaning anoestria of sows (experimental group no. 5). These parameters were evaluated: dynamics of oestrus onset within five, and/or ten, days after weaning, average length of the weaning--first insemination interval, conception rate after the first insemination in dependence on terminated deliveries and parameters of piglet litter. Cloprostenol application did not have a statistically significant effect on the evaluated reproductive parameters. The percentage of multiparous, and/or primiparous, sows in which the oestrus onset was not detected by the 10th day after weaning, did not show any large differences in the various experimental and control groups (17.09 vs. 16.55%, 23.53 vs. 32.56%, 13.66 vs. 18.13%, 29.54 vs. 30.30%; P > 0.05). On the farm with regular occurrence of post-weaning anoestria there were 73.81% of primiparous sows with oestrus onset after cloprostenol instillation and 71.43% primiparous sows without treatment.(ABSTRACT TRUNCATED AT 250 WORDS)
氯前列醇是一种前列腺素F2α类似物，曾用于捷克斯洛伐克的Oestrophan ing. Spofa制剂，现对其一种新的非传统用途进行了测试。在一组456头实验母猪和434头对照母猪中，跟踪观察了氯前列醇对仔猪断奶后母猪繁殖参数的影响。在五个部分观察中测试了单次肌内注射氯前列醇的效果：给经产母猪在断奶当天注射175微克（实验组1），断奶后第1天注射（组2），断奶后第1天注射500微克（组3）；给初产母猪在断奶后第1天注射500微克（组4）。组4所用的处理方法也应用于42头初产母猪，这些母猪所在农场经常出现母猪断奶后乏情（实验组5）。评估了以下参数：断奶后5天和/或10天内发情开始的动态情况、断奶至首次输精间隔的平均长度、首次输精后的受胎率（取决于分娩是否结束）以及仔猪窝参数。氯前列醇的应用对所评估的繁殖参数没有统计学上的显著影响。在断奶后第10天仍未检测到发情的经产和/或初产母猪的百分比，在各个实验组和对照组中没有显示出任何大的差异（17.09%对16.55%，23.53%对32.56%，13.66%对18.13%，29.54%对30.30%；P>0.05）。在经常出现断奶后乏情的农场中，注射氯前列醇后有73.81%的初产母猪发情，未处理的初产母猪为71.43%。（摘要截取自250词）
