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[免疫缺陷状态与肾小球肾炎及肾病综合征患者糖皮质激素治疗的疗效]

[The immunodeficiency state and the efficacy of the glucocorticoid therapy of patients with glomerulonephritis and the nephrotic syndrome].

作者信息

Kolesnyk M O, Dorets'kyĭ V V

出版信息

Lik Sprava. 1992 Nov-Dec(11-12):53-5.

PMID:1292222
Abstract

Results are compared of glucocorticoid treatment of proliferative, mesangioproliferative and membraneous types of glomerulonephritis with initial levels of T- and B-lymphocytes. Five types of immunodeficiency states were distinguished different frequency of the latter in various types of glomeruli involvement. It was found that glucocorticoid therapy of nephritis is most efficient in cases when the initial number of T-lymphocytes was within normal limits while the content of B-lymphocytes was increased.

摘要

将增殖性、系膜增生性和膜性肾小球肾炎的糖皮质激素治疗结果与T淋巴细胞和B淋巴细胞的初始水平进行了比较。区分了五种免疫缺陷状态,后者在各种类型的肾小球受累中的频率不同。结果发现,当T淋巴细胞的初始数量在正常范围内而B淋巴细胞的含量增加时,糖皮质激素治疗肾炎最为有效。

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