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The att locus of Rhodococcus fascians strain D188 is essential for full virulence on tobacco through the production of an autoregulatory compound.通过产生一种自调控化合物，法氏红球菌D188菌株的att位点对于其在烟草上的完全毒力至关重要。
Mol Microbiol. 2001 Oct;42(1):13-28. doi: 10.1046/j.1365-2958.2001.02615.x.
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Terminal proteins essential for the replication of linear plasmids and chromosomes in Streptomyces.链霉菌中线性质粒和染色体复制所必需的末端蛋白。
Genes Dev. 2001 Jun 15;15(12):1518-27. doi: 10.1101/gad.896201.
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Characterization of the 450-kb linear plasmid in a polychlorinated biphenyl degrader, Rhodococcus sp. strain RHA1.多氯联苯降解菌红球菌属RHA1菌株中450 kb线性质粒的特性分析
Appl Environ Microbiol. 2001 May;67(5):2021-8. doi: 10.1128/AEM.67.5.2021-2028.2001.
4
Genomic sequence and transcriptional analysis of a 23-kilobase mycobacterial linear plasmid: evidence for horizontal transfer and identification of plasmid maintenance systems.一个23千碱基分枝杆菌线性质粒的基因组序列与转录分析：水平转移的证据及质粒维持系统的鉴定
J Bacteriol. 2001 Apr;183(7):2157-64. doi: 10.1128/JB.183.7.2157-2164.2001.
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Integrated structures of the linear plasmid SCP1 in two bidirectional donor strains of Streptomyces coelicolor A3(2).天蓝色链霉菌A3(2)的两个双向供体菌株中线性质粒SCP1的整合结构
Mol Gen Genet. 2001 Jan;264(5):634-42. doi: 10.1007/s004380000349.
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Identification of two linear plasmids in the actinomycete Planobispora rosea.
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The terminal structures of linear plasmids from Rhodococcus opacus.
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Two nearly identical aromatic compound hydrolase genes in a strong polychlorinated biphenyl degrader, Rhodococcus sp. strain RHA1.在高效多氯联苯降解菌红球菌属菌株RHA1中发现的两个几乎完全相同的芳香族化合物水解酶基因。
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Microbial linear plasmids.微生物线性质粒。
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红平红球菌BD2 210千碱基线性质粒的完整核苷酸序列和遗传组织

Complete nucleotide sequence and genetic organization of the 210-kilobase linear plasmid of Rhodococcus erythropolis BD2.

作者信息

Stecker Christiane, Johann Andre, Herzberg Christina, Averhoff Beate, Gottschalk Gerhard

机构信息

Department Biologie I, Bereich Genetik und Mikrobiologie, Ludwig-Maximilians-Universität München, Maria-Ward-Strasse 1a, D-80638 Munich, Germany.

出版信息

J Bacteriol. 2003 Sep;185(17):5269-74. doi: 10.1128/JB.185.17.5269-5274.2003.

DOI:10.1128/JB.185.17.5269-5274.2003
PMID:12923100
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC180976/
Abstract

The complete nucleotide sequence of the linear plasmid pBD2 from Rhodococcus erythropolis BD2 comprises 210,205 bp. Sequence analyses of pBD2 revealed 212 putative open reading frames (ORFs), 97 of which had an annotatable function. These ORFs could be assigned to six functional groups: plasmid replication and maintenance, transport and metalloresistance, catabolism, transposition, regulation, and protein modification. Many of the transposon-related sequences were found to flank the isopropylbenzene pathway genes. This finding together with the significant sequence similarities of the ipb genes to genes of the linear plasmid-encoded biphenyl pathway in other rhodococci suggests that the ipb genes were acquired via transposition events and subsequently distributed among the rhodococci via horizontal transfer.

摘要

红平红球菌BD2的线性质粒pBD2的完整核苷酸序列包含210,205个碱基对。对pBD2的序列分析揭示了212个推定的开放阅读框（ORF），其中97个具有可注释的功能。这些ORF可分为六个功能组：质粒复制与维持、转运与金属抗性、分解代谢、转座、调控和蛋白质修饰。发现许多与转座子相关的序列位于异丙苯途径基因的侧翼。这一发现以及异丙苯基因与其他红球菌中线性质粒编码的联苯途径基因的显著序列相似性表明，异丙苯基因是通过转座事件获得的，随后通过水平转移在红球菌之间分布。