多中心研究中膝关节软骨体积的磁共振成像测量
Magnetic resonance imaging measurement of knee cartilage volume in a multicentre study.
作者信息
Morgan S R, Waterton J C, Maciewicz R A, Leadbetter J E, Gandy S J, Moots R J, Creamer P, Nash A F P
机构信息
AstraZeneca, Macclesfield, UK.
出版信息
Rheumatology (Oxford). 2004 Jan;43(1):19-21. doi: 10.1093/rheumatology/keg426. Epub 2003 Aug 15.
OBJECTIVE
To investigate the variability between different high-field scanners in magnetic resonance imaging (MRI) measurement of knee cartilage volume in healthy female volunteers.
METHODS
Five volunteers had both knees scanned using three different MRI scanners. Cartilage volume in each compartment was measured from the images by image segmentation. The data were analysed using analysis of variance models.
RESULTS
The mean total cartilage volume of the 10 knees scanned at three different centres was 16.15, 16.40 and 15.63 ml for the Siemens, GE and Philips scanners respectively. Small systematic differences were seen in the total knee cartilage volume results.
CONCLUSIONS
Although there were small systematic differences in knee cartilage volume, the three MRI scanners gave broadly similar results.
目的
研究不同高场强扫描仪在健康女性志愿者膝关节软骨体积磁共振成像（MRI）测量中的变异性。
方法
5名志愿者使用三种不同的MRI扫描仪对双膝进行扫描。通过图像分割从图像中测量每个关节腔的软骨体积。使用方差分析模型对数据进行分析。
结果
在三个不同中心扫描的10个膝关节中，西门子、通用电气和飞利浦扫描仪的平均总软骨体积分别为16.15、16.40和15.63毫升。在全膝关节软骨体积结果中观察到较小的系统差异。
结论
尽管膝关节软骨体积存在较小的系统差异，但这三种MRI扫描仪得出的结果大致相似。
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