Wongkitisophon Kitti, Phupong Vorapong, Yamasmit Waralak, Pansin Pongsak, Tannirandorn Yuen, Charoenvidhya Dhiraphongs
Department of Obstetrics and Gynecology, Faculty of Medicine, Chulalongkorn University, Bangkok 10330, Thailand.
J Med Assoc Thai. 2003 Jun;86(6):529-34.
To determine whether 4-hour urine protein value correlates with 24-hour urine protein value in women with hypertensive disorders in pregnancy.
Cross-sectional study was performed in 38 in-patient pregnant women who were initially diagnosed as having hypertensive disorders in pregnancy. Urine samples were collected within 24 hours in 2 successive periods: the first 4-hour and the next 20-hour urine, in separate containers. The urine volume, urine protein and creatinine concentrations were thus separately measured. The 4- and 24-hour urine proteins were calculated and the correlation between both groups was determined by simple linear regression analysis.
A total of 38 patients were recruited into the study, 26 had mild preeclampsia, 5 had severe preeclampsia, and 7 had superimposed preeclampsia. The result of the 4-hour urine protein was found to correlate with those of the 24-hour urine protein for patients with hypertensive disorders in pregnancy (p < 0.001).
Total protein values of 4-hour samples positively correlated with values of 24-hour samples of patients with hypertensive disorders in pregnancy. This might be modified and used for urine protein collection in outpatients to improve the compliance.
确定妊娠高血压疾病女性的4小时尿蛋白值与24小时尿蛋白值是否相关。
对38例最初诊断为妊娠高血压疾病的住院孕妇进行横断面研究。在连续24小时内分两个阶段收集尿液样本：最初4小时和接下来20小时的尿液，分别收集于不同容器中。由此分别测量尿量、尿蛋白和肌酐浓度。计算4小时和24小时尿蛋白量，并通过简单线性回归分析确定两组之间的相关性。
共有38例患者纳入研究，其中26例为轻度子痫前期，5例为重度子痫前期，7例为子痫前期合并症。发现妊娠高血压疾病患者的4小时尿蛋白结果与24小时尿蛋白结果相关（p<0.001）。
妊娠高血压疾病患者4小时样本的总蛋白值与24小时样本的值呈正相关。这可能需要改进并用于门诊患者的尿蛋白收集，以提高依从性。
