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[多哥的布鲁里溃疡:一项医院研究]

[Buruli ulcer in Togo: a hospital study].

作者信息

James Komlavi, Attipou Komla Klussé, James Yaovi Edem, Blakime Massalou, Tignokpa Napo, Abete Bawubadi

机构信息

Service de chirurgie générale A, CHU-Tokoin, BP 57, Lomé, Togo.

出版信息

Sante. 2003 Jan-Mar;13(1):43-7.

Abstract

Buruli ulcer is an emerging disease with a high prevalence in many West African countries neighbouring Togo. The aim of the present study is to assess the situation in Togolese hospitals. It was conducted for 2 years (between January 2000 and December 2001) based on the Buruli ulcer record files set up in Togolese hospitals, with a view to analyse the incidence of the disease, its characteristics in the patients and its topographic distribution in relation to their environment. During this period, 180 patients were recorded, 120 of whom were male and 18 female. The average age was 20.7 years and 20.6% of the cases were children. Lower limbs were more affected (153), followed by upper limbs (20), trunk (5), head and neck (2). Large ulcerative lesions were recorded in 11.11% of cases (n = 20), localised in 7.5% of the patients (n = 143), diffuse or metastatic in 9.4% of cases. No pre-ulcerative lesion was found. An increase in the incidence of the disease was observed from one year to the other while cases were notified in new care centres. Three risk areas were identified according to the origin of the patients : the laguna area of the coast, marshy inland areas where market crops and rice are cultivated and river valley areas. The study revealed that Buruli ulcer cases treated in Togolese hospitals were increasing year after year. A morbidity study is necessary to assess the importance of the disease on a national scale.

摘要

布氏杆菌溃疡是一种在多哥周边许多西非国家中高流行率的新兴疾病。本研究的目的是评估多哥医院的情况。该研究基于多哥医院建立的布氏杆菌溃疡记录文件进行了两年(2000年1月至2001年12月),旨在分析该疾病的发病率、患者特征及其与环境相关的地形分布。在此期间,记录了180名患者,其中男性120名,女性18名。平均年龄为20.7岁,20.6%的病例为儿童。下肢受影响更严重(153例),其次是上肢(20例)、躯干(5例)、头颈部(2例)。11.11%的病例(n = 20)记录有大溃疡性病变,7.5%的患者(n = 143)病变局限,9.4%的病例为弥漫性或转移性病变。未发现溃疡前期病变。随着新的护理中心报告病例,观察到该疾病的发病率逐年上升。根据患者来源确定了三个风险区域:沿海泻湖地区、种植经济作物和水稻的内陆沼泽地区以及河谷地区。该研究表明,多哥医院治疗的布氏杆菌溃疡病例逐年增加。有必要进行发病率研究以评估该疾病在全国范围内的重要性。

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