Rutter Carolyn M, Miglioretti Diana L
Group Health Cooperative, Center for Health Studies, 1730 Minor Ave Ste. 1600, Seattle, WA 98101, USA.
Biostatistics. 2003 Jan;4(1):97-107. doi: 10.1093/biostatistics/4.1.97.
This article presents a method for estimating the accuracy of psychological screening scales using receiver operating characteristic curves and associated statistics. Screening scales are typically semicontinuous within a known range with distributions that are nearly symmetric when the target condition is present and highly skewed when the condition is absent. We model screening scale outcomes using truncated normal distributions that accommodate these different distributional shapes and use subject-specific random effects to adjust for multiple assessments within individuals. Using the proposed model, we estimate the accuracy of the Symptom Checklist as a measure of major depression from a repeatedly screened sample of patients.
本文提出了一种使用接收者操作特征曲线及相关统计量来估计心理筛查量表准确性的方法。筛查量表在已知范围内通常是半连续的，当存在目标状况时其分布近似对称，而当不存在该状况时则高度偏态。我们使用截断正态分布对筛查量表结果进行建模，以适应这些不同的分布形状，并使用个体特定的随机效应来调整个体内部的多次评估。使用所提出的模型，我们从反复筛查的患者样本中估计症状清单作为重度抑郁症测量指标的准确性。
