Hue B, Pelhate M, Callec J J, Chanelet J
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Synaptic action of 4-aminopyridine (4-AP) has been studied in the sixth abdominal ganglion of the cockroach. Our results show that 4-AP has a strong excitatory effect on the ganglion and its seems that it depolarizes as well the pre and postsynaptic membranes. The threshold concentration is about 10(-5) M.
已在蟑螂的第六腹神经节中研究了4-氨基吡啶(4-AP)的突触作用。我们的结果表明,4-AP对神经节有强烈的兴奋作用,并且它似乎使突触前膜和突触后膜都发生了去极化。阈值浓度约为10^(-5) M。