Lassaletta Luis, Patrón Mercedes, Olóriz Javier, Pérez Rosa, Gavilán Javier
Department of Otolaryngology, University Hospital, Paseo de la Castellana, 261, 28046 Madrid, Spain.
Auris Nasus Larynx. 2003 Aug;30(3):287-90. doi: 10.1016/s0385-8146(03)00055-5.
Ceruminous gland tumours are infrequent lesions of the external auditory canal (EAC). Controversy still exists about nomenclature, classification, tissue of origin, and accurate diagnosis of these tumours. We present three cases of ceruminous gland tumours, including benign eccrine cylindroma, ceruminous adenoma, and adenoid cystic carcinoma. Superficial biopsy led to an initial erroneous diagnosis of adenocarcinoma in the latter. All cases were positive for cytokeratin and S-100 protein, supporting a ceruminous gland origin. The benign eccrine cylindroma should be included in the ceruminous gland tumour classification. A wide excisional biopsy should be performed in every EAC lesion. The terms 'ceruminoma' and 'cylindroma' should be avoided.
耵聍腺肿瘤是外耳道(EAC)的罕见病变。关于这些肿瘤的命名、分类、起源组织及准确诊断仍存在争议。我们报告3例耵聍腺肿瘤,包括良性小汗腺圆柱瘤、耵聍腺瘤和腺样囊性癌。后者经浅表活检最初误诊为腺癌。所有病例的细胞角蛋白和S-100蛋白均呈阳性,支持其起源于耵聍腺。良性小汗腺圆柱瘤应纳入耵聍腺肿瘤分类。对于每例EAC病变均应进行广泛切除活检。应避免使用“耵聍瘤”和“圆柱瘤”这两个术语。