Schmid Daniel T, Kneifel Stefan, Stoeckli Sandro J, Padberg Barbara-C, Merrill Griff, Goerres Gerhard W
Division of Nuclear Medicine, University Hospital Zurich, Raemistrasse 100, 8091 Zurich, Switzerland.
Eur Radiol. 2003 Sep;13(9):2119-21. doi: 10.1007/s00330-002-1619-4. Epub 2002 Aug 30.
We report the case of a 68-year-old patient with a known paravertebral malignant schwannoma, sent to us for postoperative staging. A combined whole-body PET/CT scan showed only poor (18)F-fluorodeoxyglucose uptake in the region of the primary tumor but distinct increased fluorodeoxyglucose uptake in the left and right thyroid gland. Thyroid sonography showed two hypoechogenic nodules. Ultrasound-guided fine-needle aspiration biopsy of one nodule showed oxyphil transformed cells, compatible with malignancy. Based on these findings, the patient underwent a subtotal thyroidectomy. Histopathology of the specimen revealed a chronic follicular Hashimoto's thyroiditis. This case demonstrates that Hashimoto's thyroiditis can mimic thyroid cancer in PET but also in sonography and fine-needle aspiration biopsy.
我们报告了一例68岁已知椎旁恶性神经鞘瘤的患者，因术后分期被转诊至我院。全身PET/CT联合扫描显示，仅原发肿瘤区域的（18）F-氟脱氧葡萄糖摄取不佳，但左右甲状腺的氟脱氧葡萄糖摄取明显增加。甲状腺超声显示两个低回声结节。对其中一个结节进行超声引导下细针穿刺活检，结果显示嗜酸性变细胞，符合恶性特征。基于这些发现，患者接受了甲状腺次全切除术。标本的组织病理学检查显示为慢性滤泡性桥本甲状腺炎。该病例表明，桥本甲状腺炎在PET检查中以及在超声和细针穿刺活检中都可能酷似甲状腺癌。
