Mikosch Peter, Würtz Franz G, Gallowitsch Hans-Jürgen, Kresnik Ewald, Lind Peter
Department of Nuclear Medicine and Special Endocrinology, PET-Center, Klagenfurt State Hospital, St. Veiterstrasse 47, A-9020 Klagenfurt.
Wien Med Wochenschr. 2003;153(3-4):89-92. doi: 10.1046/j.1563-258x.2003.02007.x.
We report on the case of a 86-year-old male patient with a rapidly growing nodule within the right lobe of the thyroid gland, which after hemithyroidectomy, turned out to be a mucosa-associated lymphoid tissue (MALT) lymphoma of the thyroid gland. In addition, Hashimoto's thyroiditis was reported in the thyroid tissue adjacent to the MALT lymphoma. During follow-up a second nodule emerged within the left lobe and, because of evidence of MALT lymphoma recurrence, F-18-FDG-PET was performed. F-18-FDG-PET imaged a clearly increased accumulation within the whole left lobe and isthmus. Thus, no differences in the degree of hypermetabolism could be imaged between the nodule and the adjacent thyroid tissue. To our knowledge, this is the first report about F-18-FDG-PET in a patient with MALT lymphoma of the thyroid. Literature search revealed only a few cases of MALT lymphomas in locations other than the thyroid gland that were studied with F-18-FDG-PET. In no case was F-18 FDG accumulation seen in the MALT lesions. However, clear F-18 FDG accumulation was reported in some patients with Hashimoto's thyroiditis. It is concluded that the intensive F-18-FDG accumulation within the whole left lobe and isthmus of the presented case was due to the coexisting Hashimoto's thyroiditis. Consequently, F-18-FDG-PET imaging does not seem to be indicated in a patient with MALT lymphoma and known Hashimoto's thyroiditis in order to evaluate the status of the MALT lymphoma.
我们报告了一例86岁男性患者，其甲状腺右叶内有一个快速生长的结节，半甲状腺切除术后，结果显示为甲状腺黏膜相关淋巴组织（MALT）淋巴瘤。此外，在与MALT淋巴瘤相邻的甲状腺组织中报告有桥本甲状腺炎。随访期间，左叶出现了第二个结节，由于有MALT淋巴瘤复发的证据，进行了F-18-FDG-PET检查。F-18-FDG-PET显示整个左叶和峡部有明显增加的放射性摄取。因此，在结节和相邻甲状腺组织之间未发现代谢亢进程度的差异。据我们所知，这是关于F-18-FDG-PET在甲状腺MALT淋巴瘤患者中的首次报告。文献检索仅发现少数甲状腺以外部位的MALT淋巴瘤病例接受了F-18-FDG-PET检查。在任何病例中，MALT病变均未见到F-18 FDG摄取。然而，一些桥本甲状腺炎患者报告有明显的F-18 FDG摄取。结论是，本病例整个左叶和峡部的强烈F-18-FDG摄取是由于并存的桥本甲状腺炎所致。因此，对于患有MALT淋巴瘤且已知有桥本甲状腺炎的患者，F-18-FDG-PET成像似乎无助于评估MALT淋巴瘤的状况。
