Franzblau Alfred, Sahakian Nancy
Associate Professor of Occupational Medicine, Department of Environmental Health Sciences, University of Michigan School of Public Health, 1420 Washington Heights, Ann Arbor, MI 48109-2029, USA.
Am J Ind Med. 2003 Sep;44(3):321-4. doi: 10.1002/ajim.10274.
Almost all reports of respiratory health effects of hydrofluoric acid are derived from industrial settings and usually involved massive and conspicuous exposures. In the present report we describe a case of adult-onset asthma immediately following use of a household rust stain remover that contained an 8-9% aqueous solution of hydrofluoric acid (HF).
This is a case-report. A literature search of hydrogen fluoride, and reactive airways dysfunction syndrome (RADS) was performed.
A previously healthy 26-year-old woman developed asthma immediately following inhalation exposure to hydrofluoric acid from a household cleaner, consistent with reactive airways dysfunction syndrome. The circumstances of exposure and possible mechanism of disease are discussed.
It is likely that this patient's use of the rust stain remover resulted in inhalation exposure to hydrofluoric acid well above any applicable standard, and hence constituted a "high level" irritant exposure capable of inducing reactive airways dysfunction syndrome. In our opinion, the presence of this concentration hydrofluoric acid in a consumer product may be unduly hazardous.
几乎所有关于氢氟酸对呼吸道健康影响的报告都来自工业环境，通常涉及大量且明显的暴露。在本报告中，我们描述了一例在使用含有8 - 9%氢氟酸（HF）水溶液的家用除锈剂后立即出现成人起病哮喘的病例。
这是一篇病例报告。对氟化氢和反应性气道功能障碍综合征（RADS）进行了文献检索。
一名此前健康的26岁女性在吸入家用清洁剂中的氢氟酸后立即出现哮喘，符合反应性气道功能障碍综合征。讨论了暴露情况和可能的发病机制。
该患者使用除锈剂很可能导致吸入的氢氟酸远远超过任何适用标准，因此构成了能够诱发反应性气道功能障碍综合征的“高水平”刺激性暴露。我们认为，消费品中存在这种浓度的氢氟酸可能具有过度的危险性。
