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氢氟酸:烧伤与全身毒性、防护措施、即时及医院治疗

Hydrofluoric Acid: Burns and Systemic Toxicity, Protective Measures, Immediate and Hospital Medical Treatment.

作者信息

Bajraktarova-Valjakova Emilija, Korunoska-Stevkovska Vesna, Georgieva Silvana, Ivanovski Kiro, Bajraktarova-Misevska Cvetanka, Mijoska Aneta, Grozdanov Anita

机构信息

Department of Prosthodontics, Faculty of Dentistry, "Ss Cyril and Methodius", University of Skopje, University Dental Clinical Centre "St Pantelejmon" "Mother Theresa" 43, 1000 Skopje, Republic of Macedonia.

Department of Oral Pathology and Periodontology, Faculty of Dentistry, "Ss Cyril and Methodius", University of Skopje, University Dental Clinical Centre "St Pantelejmon" "Mother Theresa" 43, 1000 Skopje, Republic of Macedonia.

出版信息

Open Access Maced J Med Sci. 2018 Nov 20;6(11):2257-2269. doi: 10.3889/oamjms.2018.429. eCollection 2018 Nov 25.

Abstract

BACKGROUND

Hydrofluoric acid is a commonly used chemical in many industrial branches, but it can also be found as an ingredient in household products such as cleaning agents. Possessing high corrosive potential, HF acid causes burns and tissue necrosis, while when absorbed and distributed through the bloodstream, its extremely high toxic potential is expressed. Acute symptoms are often followed by pain, particularly in the case of skin burns, which intensiveness does not often correlate with the expressiveness of the clinical findings. Even exposure to low-concentrated solutions or gasses, or low-doses of high-concentrated acid, may provoke delayed systemic disorder which may eventually have a lethal outcome.

AIM

Therefore, having information regarding the possible hazardous effects of hydrofluoric acid usage, a variety of symptoms, as well as a treatment approach, is of great importance in the case of HF exposure.

METHODS

Available scientific articles published in literature databases, scientific reports and governmental recommendations from the internet websites, written in English, using the following search terms "Hydrofluoric acid, skin burns, eye injury, ingestion, inhalation, systemic toxicity, decontamination, antidote, medical treatment" have been reviewed.

RESULTS

This review is useful not only for physicians but for everyone who may come in contact with a person exposed to HF acid.

CONCLUSION

It highlights the mechanism of action, presents the acute and chronic symptoms, personal and general protective measures and devices that should be used, as well as decontamination procedures, immediate, antidote and hospital medical treatment.

摘要

背景

氢氟酸是许多工业部门常用的化学品,但它也可作为清洁剂等家用产品的成分被发现。氢氟酸具有高腐蚀性,会导致烧伤和组织坏死,而当它通过血液吸收和分布时,其极高的毒性就会显现出来。急性症状通常伴有疼痛,尤其是皮肤烧伤的情况,疼痛程度往往与临床症状的表现不相关。即使接触低浓度溶液或气体,或低剂量的高浓度酸,也可能引发延迟性全身紊乱,最终可能导致致命后果。

目的

因此,了解氢氟酸使用可能产生的有害影响、各种症状以及治疗方法,对于氢氟酸暴露情况非常重要。

方法

对文献数据库中发表的现有科学文章、科学报告以及互联网网站上的政府建议进行了综述,这些文献均为英文撰写,使用了以下搜索词:“氢氟酸、皮肤烧伤、眼损伤、摄入、吸入、全身毒性、去污、解毒剂、医疗治疗”。

结果

本综述不仅对医生有用,对任何可能接触到氢氟酸暴露者的人也有用。

结论

它突出了作用机制,呈现了急性和慢性症状、应使用的个人和一般防护措施及设备,以及去污程序、即时处理、解毒剂和医院医疗治疗。

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