Al-Omran Mohammed, Mamdani Muhammad, McLeod Robin S
Institute for Clinical Evaluative Sciences, Toronto, Ont.
Can J Surg. 2003 Aug;46(4):263-8.
To describe the epidemiology of acute appendicitis in the Province of Ontario, we carried out a retrospective population-based cohort study of all patients with acute appendicitis.
Using hospital discharge abstracts of patients with acute appendicitis from all acute care hospitals in Ontario for the fiscal years 1991-1998 coded for the Canadian Institute for Health Information, we studied the demographic features, particularly age and sex, length of hospital stay (LOS), incidence, and seasonal variation of acute appendicitis.
During the observation period, 65,675 cases of acute appendicitis occurred in Ontario. Of these, 58% of the patients were male and 35.5% had perforation. The mean (and standard deviation [SD]) LOS for patients with perforation was 6.2 (5.3) days versus 3 (1.8) days for patients with no perforation (p < 0.001). The age-specific incidence of acute appendicitis followed a similar pattern for males and females, but males had higher rates in all age groups. The incidence was highest in those aged 10-19 years. The annual age and sex-adjusted incidence of acute appendicitis was 75 per 100,000 population. The female:male age-adjusted rate ratio was 1:1.4. During the study period, the rate of acute appendicitis decreased by 5.1%, but the rate of appendicitis with perforation increased by 13%. A significant seasonal effect was also observed, with the rate of acute appendicitis being higher in the summer months.
Appendicitis is more common in males, in those aged 10-19 years, and during the summer months. The frequency of acute appendicitis appears to be decreasing whereas the proportion of cases with perforation appears to be increasing. This may reflect a change in the population structure in Ontario and restrictions placed on the patient access to the health care system.
为描述安大略省急性阑尾炎的流行病学情况，我们对所有急性阑尾炎患者进行了一项基于人群的回顾性队列研究。
利用安大略省所有急症医院1991 - 1998财政年度急性阑尾炎患者的医院出院摘要，这些摘要由加拿大卫生信息研究所编码，我们研究了急性阑尾炎的人口统计学特征，尤其是年龄和性别、住院时间（LOS）、发病率以及季节性变化。
在观察期内，安大略省共发生65675例急性阑尾炎病例。其中，58%的患者为男性，35.5%的患者发生穿孔。穿孔患者的平均（及标准差[SD]）住院时间为6.2（5.3）天，未穿孔患者为3（1.8）天（p < 0.001）。急性阑尾炎的年龄别发病率在男性和女性中遵循相似模式，但在所有年龄组中男性发病率更高。发病率在10 - 19岁人群中最高。急性阑尾炎的年度年龄和性别调整发病率为每10万人口75例。女性与男性的年龄调整发病率比为1:1.4。在研究期间，急性阑尾炎发病率下降了5.1%，但穿孔性阑尾炎发病率上升了13%。还观察到显著的季节性影响，夏季急性阑尾炎发病率更高。
阑尾炎在男性、10 - 19岁人群以及夏季更为常见。急性阑尾炎的发病率似乎在下降，而穿孔病例的比例似乎在上升。这可能反映了安大略省人口结构的变化以及患者获得医疗保健系统服务的限制。
