Addiss D G, Shaffer N, Fowler B S, Tauxe R V
Division of Bacterial Diseases, Center for Infectious Diseases, Centers for Disease Control, Atlanta, GA 30333.
Am J Epidemiol. 1990 Nov;132(5):910-25. doi: 10.1093/oxfordjournals.aje.a115734.
To describe the epidemiology of appendicitis and appendectomy in the United States, the authors analyzed National Hospital Discharge Survey data for the years 1979-1984. Approximately 250,000 cases of appendicitis occurred annually in the United States during this period, accounting for an estimated 1 million hospital days per year. The highest incidence of primary positive appendectomy (appendicitis) was found in persons aged 10-19 years (23.3 per 10,000 population per year); males had higher rates of appendicitis than females for all age groups (overall rate ratio, 1.4:1). Racial, geographic, and seasonal differences were also noted. Appendicitis rates were 1.5 times higher for whites than for nonwhites, highest (15.4 per 10,000 population per year) in the west north central region, and 11.3% higher in the summer than in the winter months. The highest rate of incidental appendectomy was found in women aged 35-44 years (43.8 per 10,000 population per year), 12.1 times higher than the rate for men of the same age. Between 1970 and 1984, the incidence of appendicitis decreased by 14.6%; reasons for this decline are unknown. A life table model suggests that the lifetime risk of appendicitis is 8.6% for males and 6.7% for females; the lifetime risk of appendectomy is 12.0% for males and 23.1% for females. Overall, an estimated 36 incidental procedures are performed to prevent one case of appendicitis; for the elderly, the preventive value of an incidental procedure is considerably lower.
为描述美国阑尾炎及阑尾切除术的流行病学特征,作者分析了1979 - 1984年的国家医院出院调查数据。在此期间,美国每年约有25万例阑尾炎病例发生,估计每年占用100万个住院日。原发性阳性阑尾切除术(阑尾炎)的发病率在10 - 19岁人群中最高(每年每10000人中有23.3例);在所有年龄组中,男性阑尾炎发病率均高于女性(总体发病率比为1.4:1)。还注意到种族、地理和季节差异。白人阑尾炎发病率是非白人的1.5倍,在西北中部地区最高(每年每10000人中有15.4例),夏季比冬季高11.3%。偶然阑尾切除术的最高发病率出现在35 - 44岁女性中(每年每10000人中有43.8例),是同年龄男性发病率的12.1倍。1970年至1984年间,阑尾炎发病率下降了14.6%;下降原因不明。生命表模型表明,男性患阑尾炎的终生风险为8.6%,女性为6.7%;男性阑尾切除术的终生风险为12.0%,女性为23.1%。总体而言,估计每进行36例偶然手术可预防1例阑尾炎;对于老年人,偶然手术的预防价值要低得多。