Koul Summon, Razdan T K, Andotra C S
Department of Chemistry, University of Jammu, Ambedkar Road, Jammu-180006, India.
J Nat Prod. 2003 Aug;66(8):1121-3. doi: 10.1021/np030070u.
Three new triterpenoids, designated as acinospesigenin-A (1), -B (2), and -C (3), isolated from the berries of Phytolacca acinosa, have been characterized as 3 beta-acetoxy-11 alpha,23-dihydroxytaraxer-14-en-28-oic acid, olean-12-en-23-al-2 beta,3 beta-dihydroxy-30-methoxycarbonyl-28-oic acid and olean-12-en-23-al-2 beta,3 beta,11 alpha-trihydroxy-30-methoxycarbonyl-28-oic acid, respectively. The compounds have shown antiedemic activity (LD(50) 10-15 mg/kg mass) in albino rats.
从商陆浆果中分离出的三种新的三萜类化合物，分别命名为商陆皂苷元-A（1）、-B（2）和-C（3），其结构分别鉴定为3β-乙酰氧基-11α,23-二羟基蒲公英赛-14-烯-28-酸、齐墩果-12-烯-23-醛-2β,3β-二羟基-30-甲氧基羰基-28-酸和齐墩果-12-烯-23-醛-2β,3β,11α-三羟基-30-甲氧基羰基-28-酸。这些化合物在白化大鼠中显示出抗水肿活性（半数致死量为10 - 15mg/kg体重）。
