Miyazawa H, Wakai T, Toshida T, Yamamoto Y, Ohta M
Department of Pediatrics, National Medical Center Hospital.
Kansenshogaku Zasshi. 1992 Oct;66(10):1416-21. doi: 10.11150/kansenshogakuzasshi1970.66.1416.
The pneumonia, sepsis and meningitis are common diseases of GBS infection in infants. There are early-onset and late-onset types in this disease, the result of the infection is unknown. M. Sugiyama reported that M9 is a new type of GBS in Japan in 1989. Analysis of GBS typing and serum specific antibody concentrations of the type are simple with new technics. By studying the infants' contamination we discovered that GBS appeared to originate from mother-infant sources. The infants were followed for a year. 52% of the infants had GBS contamination in their throat or stool. The most common type was Ia, followed by III, JM9 and NT6. Those types without III type had been present for more than 9 months in the infant. The contamination term of Ia or III type in infants correlated with the blood specific antibody concentration of the type.
肺炎、败血症和脑膜炎是婴儿感染B族链球菌(GBS)的常见疾病。该疾病有早发型和晚发型,感染结果尚不清楚。杉山茂于1989年在日本报道M9是GBS的一种新型。采用新技术对GBS进行分型分析以及该型血清特异性抗体浓度分析较为简单。通过研究婴儿的感染情况,我们发现GBS似乎源自母婴传播途径。对婴儿进行了一年的跟踪。52%的婴儿咽喉或粪便中有GBS感染。最常见的类型是Ia型,其次是III型、JM9型和NT6型。那些没有III型的类型在婴儿体内已存在9个月以上。婴儿体内Ia型或III型的感染期与该型血液特异性抗体浓度相关。