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孕期进行B族链球菌筛查是否合理?

Is group B streptococcal screening during pregnancy justified?

作者信息

Easmon C S, Hastings M J, Neill J, Bloxham B, Rivers R P

出版信息

Br J Obstet Gynaecol. 1985 Mar;92(3):197-201. doi: 10.1111/j.1471-0528.1985.tb01081.x.

DOI:10.1111/j.1471-0528.1985.tb01081.x
PMID:3884034
Abstract

Twenty-eight per cent of women investigated during pregnancy were carriers of group B streptococci (GBS). The use of broth enrichment was the most significant factor in determining GBS carriage rates. GBS carriage decreased during pregnancy. Transmission of GBS from mother to baby was related to vaginal carriage but rectal carriage in pregnancy was the best predictor of maternal carriage at term. Rectal and vaginal swabs taken at 28 and 36 weeks correctly predicted 92% of intrapartum GBS carriage. Although accurate prediction of intrapartum GBS carriage is possible, mass screening for GBS in pregnancy is unlikely to be cost-effective in those countries with a low incidence of neonatal GBS sepsis.

摘要

在孕期接受检查的女性中,28%是B族链球菌(GBS)携带者。使用肉汤增菌法是决定GBS携带率的最重要因素。孕期GBS携带率会下降。GBS从母亲传播给婴儿与阴道携带有关,但孕期直肠携带是足月时母亲携带情况的最佳预测指标。在孕28周和36周采集的直肠和阴道拭子能正确预测92%的产时GBS携带情况。尽管准确预测产时GBS携带情况是可能的,但在新生儿GBS败血症发病率较低的国家,孕期对GBS进行大规模筛查不太可能具有成本效益。

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