Ambrus J L, Hoffman M, Ambrus C M, Hreshchyshyn M M, Moore D, Munschauer F E
State University of New York, Department of Internal Medicine, Buffalo.
J Med. 1992;23(6):369-88.
This review summarizes basic pathophysiology, epidemiology, classification and theories on the etiology of osteoporoses. Diagnostic, preventative and therapeutic aspects are discussed including the use of hormones and hormone analogues (estrogen, progestins, calcitonins, anabolic steroids), calcium, fluoride, bisphosphonates, vitamins D and their metabolites and the recently proposed "coherence therapy". Reference is made to new compounds under study including imidazoquinazolinones, methylxanthines and benzothiophenes.
本综述总结了骨质疏松症的基本病理生理学、流行病学、分类及病因学理论。文中讨论了诊断、预防和治疗方面的内容，包括激素和激素类似物（雌激素、孕激素、降钙素、合成代谢类固醇）、钙、氟化物、双膦酸盐、维生素D及其代谢产物的使用，以及最近提出的“连贯疗法”。文中还提及了正在研究的新化合物，包括咪唑喹唑啉酮、甲基黄嘌呤和苯并噻吩。
