19例鼻腔恶性黑色素瘤的临床分析
[Clinical analysis of 19 patients with malignant melanoma of the nasal cavity].
作者信息
Wei Rui, Jiang Wei-hong, Shen Liang-fang
机构信息
Department of Radiation Oncology, Department of Otolaryngology, Xiangya Hospital, Central South University, Changsha 410008, China.
出版信息
Hunan Yi Ke Da Xue Xue Bao. 2003 Apr;28(2):121-2.
OBJECTIVE
To explore the pathology, clinical characteristics and treatment of patients with malignant melanoma of the nasal cavity.
METHODS
From September, 1988 to July, 2001, 19 patients with malignant melanoma of the nasal cavity were treated in our hospital. All the patients were confirmed by histopathology. The most common symptoms were nasal obstruction and epistaxis. All the patients were treated with surgery(S), 6 with S plus radiotherapy (R), 2 with S plus R plus chemotherapy (C), 3 with S plus C.
RESULTS
Seven cases survived for 8 months to 13 years. The survival rates of 1, 3, 5 years were 64.7%, 42.85%, 30.76% respectively.
CONCLUSION
Malignant melanoma of the nasal cavity has an aggressive behavior and is easy to recur. S + R is an effective method.
目的
探讨鼻腔恶性黑色素瘤患者的病理、临床特征及治疗方法。
方法
1988年9月至2001年7月，我院收治19例鼻腔恶性黑色素瘤患者。所有患者均经组织病理学确诊。最常见的症状为鼻塞和鼻出血。所有患者均接受手术治疗（S），6例接受S加放疗（R），2例接受S加R加化疗（C），3例接受S加C。
结果
7例患者存活8个月至13年。1年、3年、5年生存率分别为64.7%、42.85%、30.76%。
结论
鼻腔恶性黑色素瘤具有侵袭性，易复发。S + R是一种有效的治疗方法。
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