[模拟钠对血液透析中透析失衡综合征的影响]
[Influence of modeling sodium on the dialysis disequilibrium syndrome in hemodialysis].
作者信息
Liu Hong, Zhu Jian-ling, Chen Xing
机构信息
Department of Nephrology, Second Xiangya Hospital, Central South University, Changsha 410011, China.
出版信息
Hunan Yi Ke Da Xue Xue Bao. 2003 Feb 28;28(1):76-8.
OBJECTIVE
To observe the influence of modeling sodium on the dialysis disequilibrium syndrome in hemodialysis.
METHODS
Sixteen patients received hemodialysis for the first time. Eight of them received the hemodialysis in the order of common sodium, modeling sodium, common sodium, and modeling sodium, whereas the other 8 patients were treated in the order of modeling sodium, common sodium, modeling sodium, and common sodium. The symptoms of the dialysis disequilibrium syndrome were observed and blood sodium concentration was examined before and after the dialysis.
RESULTS
The main symptoms of the dialysis disequilibrium syndrome were headache, nausea, vomiting, hypertension, and dyspnea. Modeling sodium hemodialysis could significantly decrease the occurrence of these symptoms (P < 0.05). The blood sodium concentration after the hemodialysis was not significantly changed compared with that before the hemodialysis (P > 0.05).
CONCLUSION
Modeling sodium hemodialysis can effectively prevent the occurrence of the dialysis disequilibrium syndrome without increasing the natrium load of the patients.
目的
观察模拟钠对血液透析中透析失衡综合征的影响。
方法
16例首次接受血液透析的患者。其中8例按照普通钠、模拟钠、普通钠、模拟钠的顺序进行血液透析，另外8例按照模拟钠、普通钠、模拟钠、普通钠的顺序进行治疗。观察透析失衡综合征的症状，并检测透析前后的血钠浓度。
结果
透析失衡综合征的主要症状为头痛、恶心、呕吐、高血压和呼吸困难。模拟钠血液透析可显著降低这些症状的发生率（P<0.05）。血液透析后的血钠浓度与透析前相比无明显变化（P>0.05）。
结论
模拟钠血液透析可有效预防透析失衡综合征的发生，且不增加患者的钠负荷。
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