Adler Robert A, Tran Mongthuong T, Petkov Valentina I
Endocrinology Section, McGuire Veterans Affairs Medical Center, Richmond, VA 23249, USA.
Mayo Clin Proc. 2003 Jun;78(6):723-7. doi: 10.4065/78.6.723.
To determine whether the Osteoporosis Self-assessment Tool (OST) can predict central bone mineral density in men, as defined by dual energy x-ray absorptiometry (DXA).
We applied the OST index to men in pulmonary (evaluated January-May 2001) and rheumatology (evaluated November 2001-March 2002) clinics at a veterans hospital. The calculated OST risk index is based on weight and age.
In 181 men, we arbitrarily defined osteoporosis as a DXA T score of -25 or less in the spine, total hip, or femoral neck. The mean age and weight of the men were 64.3 years and 91.2 kg; 15.6% had osteoporosis by DXA. The OST index ranged from -5 to 19, from which we categorized risk as follows: low, 4 or greater; moderate,-1 to 3; and high, -2 or less. Only 2.0% of men with a low-risk OST index had osteoporosis, whereas 27.0% with a moderate risk and 72.7% with a high risk had osteoporosis. Using an OST cutoff score of 3, we predicted osteoporosis with a sensitivity of 93% and a specificity of 66%. When patients were studied by age in decades, race, or current glucocorticoid use, the predictive value of the OST was maintained.
The OST is an easy method to predict osteoporosis by DXA.
确定骨质疏松症自我评估工具（OST）能否预测男性的中央骨矿物质密度，该密度通过双能X线吸收法（DXA）测定。
我们将OST指数应用于一家退伍军人医院肺病科（2001年1月至5月评估）和风湿病科（2001年11月至2002年3月评估）的男性患者。计算得出的OST风险指数基于体重和年龄。
在181名男性中，我们将脊柱、全髋或股骨颈的DXA T值小于或等于-2.5定义为骨质疏松症。这些男性的平均年龄和体重分别为64.3岁和91.2千克；15.6%的患者经DXA诊断为骨质疏松症。OST指数范围为-5至19，我们将风险分类如下：低风险，指数为4或更高；中度风险，指数为-1至3；高风险，指数为-2或更低。OST指数为低风险的男性中只有2.0%患有骨质疏松症，而中度风险者为27.0%，高风险者为72.7%。使用OST临界值为3时，我们预测骨质疏松症的敏感度为93%，特异度为66%。按年龄十年分组、种族或当前糖皮质激素使用情况对患者进行研究时，OST的预测价值保持不变。
OST是一种通过DXA预测骨质疏松症的简便方法。
