Zhang Hong-Mei, Liu Hui-Ling, Wang Xuan, Chen Wei, Chen Dan, Zhang Zhong-Zhi, Wang Han-Ming
Department of Endocrinology, The Central Hospital of Wuhan, No.26, Shengli Street, Jiang'an District, 430014, Wuhan, China.
Hubei Integrated Traditional Chinese and Western Medicine Hospital, Hubei University of Chinese Medicine Affiliated Hospital, No 5, New Tian-Men Dun Road,430015, Wuhan, China.
Open Med (Wars). 2016 Jun 23;11(1):190-195. doi: 10.1515/med-2016-0036. eCollection 2016.
Early detection of high-risk population for osteoporosis is the key to preventing this disease.
In this cross-sectional study a continuous sample of 270 women and 89 men (age: 20-90 years) was divided into four groups by age (≤ 55 or > 55 years) and sex. Participants completed the IOF test. Low-, medium-, and high-risk grades were defined by an OSTA index of greater than -1, -1 to -4, and less than -4, respectively.
Most participants were categorized in the low-risk group (240 people, 66.9%), followed by the medium-risk (102 people, 28.4%) and high-risk groups (17 people, 4.7%). Compared to women, men in both age groups had significantly higher OSTA index and greater numbers of positive answers on the IOF test. 64.3% individuals were susceptible to osteoporosis risk (≥1 positive answers on the IOF test). Multiple regression analysis demonstrated that family history of fragility fracture (OR: 0.503, 95% CI: 0.26-0.97), height loss exceeding 3 cm (OR: 2.51, 95% CI: 1.55-4.05), and earlier menopause (OR: 0.434, 95% CI: 0.19-0.97) were associated with higher risk grades.
Combined use of the OSTA and IOF test is a simple and effective method for assessing the risk of osteoporosis.
早期发现骨质疏松高危人群是预防该疾病的关键。
在这项横断面研究中，连续抽取270名女性和89名男性（年龄20 - 90岁）样本，按年龄（≤55岁或>55岁）和性别分为四组。参与者完成国际骨质疏松基金会（IOF）测试。低、中、高风险等级分别由骨质疏松自我筛查工具（OSTA）指数大于 -1、-1至 -4和小于 -4定义。
大多数参与者被归类为低风险组（240人，66.9%），其次是中风险组（102人，28.4%）和高风险组（17人，4.7%）。与女性相比，两个年龄组的男性OSTA指数显著更高，在IOF测试中的阳性回答数量更多。64.3%的个体易患骨质疏松风险（IOF测试中≥1个阳性回答）。多元回归分析表明，脆性骨折家族史（比值比：0.503，95%置信区间：0.26 - 0.97）、身高降低超过3厘米（比值比：2.51，95%置信区间：1.55 - 4.05）和更早绝经（比值比：0.434，95%置信区间：0.19 - 0.97）与更高风险等级相关。
联合使用OSTA和IOF测试是评估骨质疏松风险的一种简单有效的方法。
