Gonmori Kunio, Yoshioka Naofumi
Department of Forensic Medicine, Akita University School of Medicine, Akita 010-8543, Japan.
Leg Med (Tokyo). 2003 Mar;5 Suppl 1:S83-6. doi: 10.1016/s1344-6223(02)00127-x.
In the past 10 years from 1991 to 2000, the number of consultations to the Japan Poison Information Center were 947 concerning mushroom poisonings. However, those from the hospital cases were not analyzed toxicologically. We examined toxicologically 20 cases (35 patients) of mushroom poisonings from 1993 to 2001. Investigation of amanita toxin poisoning was requested in 19 cases. We could detect the amanita toxin, amanitin, and phalloidin, in two cases, which resulted in concluding the cause of death. A fatal case by the magic mushroom poisoning was analyzed in the blood, urine, and mushroom, and we detected the hallucinogenic substances from the body fluids and ingested mushrooms. We report the results of our examinations, and point out the usefulness of the examination of the mushroom itself and biological samples toxicologically for forensic practice.
在1991年至2000年的过去10年里,日本中毒信息中心接到的关于蘑菇中毒的咨询有947起。然而,来自医院病例的咨询未进行毒理学分析。我们对1993年至2001年期间的20例(35名患者)蘑菇中毒病例进行了毒理学检查。其中19例被要求对鹅膏毒素中毒进行调查。我们在两例中检测到了鹅膏毒素、鹅膏毒肽和鬼笔环肽,从而确定了死亡原因。对一例因神奇蘑菇中毒导致的死亡病例进行了血液、尿液和蘑菇的分析,我们从体液和摄入的蘑菇中检测到了致幻物质。我们报告了检查结果,并指出对蘑菇本身和生物样本进行毒理学检查在法医实践中的有用性。