蘑菇中毒所致急性肝衰竭：一例报告并文献复习
Acute liver failure caused by mushroom poisoning: a case report and review of the literature.
作者信息
Erden Abdulsamet, Esmeray Kübra, Karagöz Hatice, Karahan Samet, Gümüşçü Hasan Hüseyin, Başak Mustafa, Cetinkaya Ali, Avcı Deniz, Poyrazoğlu Orhan Kürşat
机构信息
Internal Medicine Department, Kayseri Training and Research Hospital, Kayseri, Turkey.
出版信息
Int Med Case Rep J. 2013 Nov 22;6:85-90. doi: 10.2147/IMCRJ.S53773. eCollection 2013.
It is estimated that there are over 5,000 species of mushrooms worldwide. Some of them are edible and some are poisonous due to containing significant toxins. In more than 95% of mushroom toxicity cases, poisoning occurs as a result of misidentification of the mushroom by an amateur mushroom hunter. The severity of mushroom poisoning may vary, depending on the geographic location where the mushroom is grown, growth conditions, the amount of toxin delivered, and the genetic characteristics of the mushroom. Amanita phalloides is the most common and fatal cause of mushroom poisoning. This mushroom contains amanitins, which are powerful hepatotoxins that inhibit RNA polymerase II in liver. Mushroom poisoning is a relatively rare cause of acute liver failure. A 63-year-old male patient was admitted to the emergency room with weakness, nausea, vomiting, and diarrhea. He reported ingesting several wild mushrooms about 36 hours earlier. In this article we report a case of lethal Amanita phalloides intoxication from stored mushrooms.
据估计，全球有超过5000种蘑菇。其中一些可食用，而有些则因含有大量毒素而有毒。在超过95%的蘑菇中毒病例中，中毒是由于业余蘑菇采集者误认蘑菇所致。蘑菇中毒的严重程度可能各不相同，这取决于蘑菇生长的地理位置、生长条件、摄入的毒素量以及蘑菇的遗传特性。毒鹅膏是蘑菇中毒最常见且致命的原因。这种蘑菇含有鹅膏毒素，它们是强大的肝毒素，可抑制肝脏中的RNA聚合酶II。蘑菇中毒是急性肝衰竭相对罕见的病因。一名63岁男性患者因虚弱、恶心、呕吐和腹泻被送往急诊室。他报告称大约36小时前食用了几种野生蘑菇。在本文中，我们报告一例因食用储存蘑菇导致的致命毒鹅膏中毒病例。
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